Literature DB >> 18937562

Activity-based probes as a tool for functional proteomic analysis of proteases.

Marko Fonović1, Matthew Bogyo.   

Abstract

Traditional proteomics methodology allows global analysis of protein abundance but does not provide information on the regulation of protein activity. Proteases, in particular, are known for their multilayered post-translational activity regulation that can lead to a significant difference between protease abundance levels and their enzyme activity. To address these issues, the field of activity-based proteomics has been established in order to characterize protein activity and monitor the functional regulation of enzymes in complex proteomes. In this review, we present structural features of activity-based probes for proteases and discuss their applications in proteomic profiling of various catalytic classes of proteases.

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Year:  2008        PMID： 18937562      PMCID： PMC2997944          DOI： 10.1586/14789450.5.5.721

Source DB:  PubMed          Journal:  Expert Rev Proteomics        ISSN： 1478-9450            Impact factor:   3.940


  92 in total

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Journal:  Nature       Date:  1997-02-20       Impact factor: 49.962

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Journal:  J Biol Chem       Date:  1997-10-03       Impact factor: 5.157

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Journal:  Proc Natl Acad Sci U S A       Date:  1997-06-24       Impact factor: 11.205

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Journal:  Proc Natl Acad Sci U S A       Date:  1987-04       Impact factor: 11.205

5.  Mechanism of ubiquitin carboxyl-terminal hydrolase. Borohydride and hydroxylamine inactivate in the presence of ubiquitin.

Authors:  C M Pickart; I A Rose
Journal:  J Biol Chem       Date:  1986-08-05       Impact factor: 5.157

6.  The use of benzyloxycarbonyl[125I]iodotyrosylalanyldiazomethane as a probe for active cysteine proteinases in human tissues.

Authors:  R W Mason; L T Bartholomew; B S Hardwick
Journal:  Biochem J       Date:  1989-11-01       Impact factor: 3.857

7.  Inactivation of interleukin-1 beta converting enzyme by peptide (acyloxy)methyl ketones.

Authors:  N A Thornberry; E P Peterson; J J Zhao; A D Howard; P R Griffin; K T Chapman
Journal:  Biochemistry       Date:  1994-04-05       Impact factor: 3.162

8.  Irreversible inhibition of serine proteases by peptide derivatives of (alpha-aminoalkyl)phosphonate diphenyl esters.

Authors:  J Oleksyszyn; J C Powers
Journal:  Biochemistry       Date:  1991-01-15       Impact factor: 3.162

9.  Inhibition of proteasome activities and subunit-specific amino-terminal threonine modification by lactacystin.

Authors:  G Fenteany; R F Standaert; W S Lane; S Choi; E J Corey; S L Schreiber
Journal:  Science       Date:  1995-05-05       Impact factor: 47.728

10.  A chemically cleavable biotinylated nucleotide: usefulness in the recovery of protein-DNA complexes from avidin affinity columns.

Authors:  M Shimkus; J Levy; T Herman
Journal:  Proc Natl Acad Sci U S A       Date:  1985-05       Impact factor: 11.205
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  55 in total

1.  An activity-based imaging probe for the integral membrane hydrolase KIAA1363.

Authors:  Jae Won Chang; Raymond E Moellering; Benjamin F Cravatt
Journal:  Angew Chem Int Ed Engl       Date:  2011-12-07       Impact factor: 15.336

2.  Nuclear cysteine cathepsin variants in thyroid carcinoma cells.

Authors:  Sofia Tedelind; Kseniia Poliakova; Amanda Valeta; Ruth Hunegnaw; Eyoel Lemma Yemanaberhan; Nils-Erik Heldin; Junichi Kurebayashi; Ekkehard Weber; Nataša Kopitar-Jerala; Boris Turk; Matthew Bogyo; Klaudia Brix
Journal:  Biol Chem       Date:  2010-08       Impact factor: 3.915

Review 3.  Pathomimetic cancer avatars for live-cell imaging of protease activity.

Authors:  Kyungmin Ji; Joshua Heyza; Dora Cavallo-Medved; Bonnie F Sloane
Journal:  Biochimie       Date:  2015-09-12       Impact factor: 4.079

4.  The Natural Product Elegaphenone Potentiates Antibiotic Effects against Pseudomonas aeruginosa.

Authors:  Weining Zhao; Ashley R Cross; Caillan Crowe-McAuliffe; Angela Weigert-Munoz; Erika E Csatary; Amy E Solinski; Joanna Krysiak; Joanna B Goldberg; Daniel N Wilson; Eva Medina; William M Wuest; Stephan A Sieber
Journal:  Angew Chem Int Ed Engl       Date:  2019-05-16       Impact factor: 15.336

5.  Affinity-based profiling of dehydrogenase subproteomes.

Authors:  Xia Ge; Daniel S Sem
Journal:  Methods Mol Biol       Date:  2012

Review 6.  Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes.

Authors:  Reik Löser; Jens Pietzsch
Journal:  Front Chem       Date:  2015-06-23       Impact factor: 5.221

7.  Finding enzymes that are actively involved in cancer.

Authors:  Matthew Bogyo
Journal:  Proc Natl Acad Sci U S A       Date:  2010-02-01       Impact factor: 11.205

Review 8.  Imaging enzymes at work: metabolic mapping by enzyme histochemistry.

Authors:  Cornelis J F Van Noorden
Journal:  J Histochem Cytochem       Date:  2010-02-01       Impact factor: 2.479

9.  Cathepsin S is activated during colitis and causes visceral hyperalgesia by a PAR2-dependent mechanism in mice.

Authors:  Fiore Cattaruzza; Victoria Lyo; Ella Jones; David Pham; James Hawkins; Kimberley Kirkwood; Eduardo Valdez-Morales; Charles Ibeakanma; Stephen J Vanner; Matthew Bogyo; Nigel W Bunnett
Journal:  Gastroenterology       Date:  2011-07-28       Impact factor: 22.682

10.  Integrative proteomic profiling of protein activity and interactions using protein arrays.

Authors:  Se-Hui Jung; Kangseung Lee; Deok-Hoon Kong; Woo Jin Kim; Young-Myeong Kim; Kwon-Soo Ha
Journal:  Mol Cell Proteomics       Date:  2012-07-26       Impact factor: 5.911
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