Literature DB >> 18931777

Isolation, structure and fatty acid synthesis inhibitory activities of platensimycin B1-B3 from Streptomyces platensis.

Chaowei Zhang1, John Ondeyka, Deborah L Zink, Bruce Burgess, Jun Wang, Sheo B Singh.   

Abstract

Platensimycins B(1)-B(3) are natural congeners of platensimycin with modest to significant changes in the benzoic acid portion of the molecule, leading to attenuation in the biological activities and thus confirming the significance of the free carboxylate for the potent activity.

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Year:  2008        PMID： 18931777     DOI： 10.1039/b810113b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  8 in total

1.  Perspectives from nearly five decades of total synthesis of natural products and their analogues for biology and medicine.

Authors:  K C Nicolaou; Stephan Rigol
Journal:  Nat Prod Rep       Date:  2020-04-22       Impact factor: 13.423

2.  Engineering of Streptomyces platensis MA7339 for overproduction of platencin and congeners.

Authors:  Zhiguo Yu; Michael J Smanski; Ryan M Peterson; Karen Marchillo; David Andes; Scott R Rajski; Ben Shen
Journal:  Org Lett       Date:  2010-04-16       Impact factor: 6.005

Review 3.  Platensimycin and platencin: Inspirations for chemistry, biology, enzymology, and medicine.

Authors:  Jeffrey D Rudolf; Liao-Bin Dong; Ben Shen
Journal:  Biochem Pharmacol       Date:  2016-11-16       Impact factor: 5.858

4.  Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies.

Authors:  Michaela Wenzel; Malay Patra; Dirk Albrecht; David Y-K Chen; K C Nicolaou; Nils Metzler-Nolte; Julia E Bandow
Journal:  Antimicrob Agents Chemother       Date:  2011-03-07       Impact factor: 5.191

5.  Total synthesis of platensimycin and related natural products.

Authors:  K C Nicolaou; Ang Li; David J Edmonds; G Scott Tria; Shelby P Ellery
Journal:  J Am Chem Soc       Date:  2009-11-25       Impact factor: 15.419

6.  A concise ring-expansion route to the compact core of platensimycin.

Authors:  Nicholas A McGrath; Emily S Bartlett; Satapanawat Sittihan; Jon T Njardarson
Journal:  Angew Chem Int Ed Engl       Date:  2009       Impact factor: 15.336

Review 7.  Bacterial terpenome.

Authors:  Jeffrey D Rudolf; Tyler A Alsup; Baofu Xu; Zining Li
Journal:  Nat Prod Rep       Date:  2021-05-26       Impact factor: 15.111

Review 8.  The use of platensimycin and platencin to fight antibiotic resistance.

Authors:  Adil M Allahverdiyev; Melahat Bagirova; Emrah Sefik Abamor; Sezen Canim Ates; Rabia Cakir Koc; Meral Miraloglu; Serhat Elcicek; Serkan Yaman; Gokce Unal
Journal:  Infect Drug Resist       Date:  2013-09-18       Impact factor: 4.003
  8 in total

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