Literature DB >> 18929664

Studying isoform-specific inositol 1,4,5-trisphosphate receptor function and regulation.

Matthew J Betzenhauser1, Larry E Wagner, Jong Hak Won, David I Yule.   

Abstract

Inositol 1,4,5-trisphosphate receptors (InsP3R) are a family of ubiquitously expressed intracellular Ca2+ channels. Isoform-specific properties of the three family members may play a prominent role in defining the rich diversity of the spatial and temporal characteristics of intracellular Ca2+ signals. Studying the properties of the particular family members is complicated because individual receptor isoforms are typically never expressed in isolation. In this article, we discuss strategies for studying Ca2+ release through individual InsP3R family members with particular reference to methods applicable following expression of recombinant InsP3R and mutant constructs in the DT40-3KO cell line, an unambiguously null InsP3R expression system.

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Year:  2008        PMID： 18929664      PMCID： PMC3069621          DOI： 10.1016/j.ymeth.2008.09.014

Source DB:  PubMed          Journal:  Methods        ISSN： 1046-2023            Impact factor:   3.608


  45 in total

1.  Lateral inhibition of inositol 1,4,5-trisphosphate receptors by cytosolic Ca(2+).

Authors:  C E Adkins; C W Taylor
Journal:  Curr Biol       Date:  1999-10-07       Impact factor: 10.834

2.  The type II inositol 1,4,5-trisphosphate receptor can trigger Ca2+ waves in rat hepatocytes.

Authors:  Keiji Hirata; Thomas Pusl; Allison F O'Neill; Jonathan A Dranoff; Michael H Nathanson
Journal:  Gastroenterology       Date:  2002-04       Impact factor: 22.682

3.  Reduced IP3 sensitivity of IP3 receptor in Purkinje neurons.

Authors:  A Fujiwara; K Hirose; T Yamazawa; M Iino
Journal:  Neuroreport       Date:  2001-08-28       Impact factor: 1.837

4.  Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum.

Authors:  Wihelma Echevarría; M Fatima Leite; Mateus T Guerra; Warren R Zipfel; Michael H Nathanson
Journal:  Nat Cell Biol       Date:  2003-05       Impact factor: 28.824

5.  Ca(2+)-sensor region of IP(3) receptor controls intracellular Ca(2+) signaling.

Authors:  T Miyakawa; A Mizushima; K Hirose; T Yamazawa; I Bezprozvanny; T Kurosaki; M Iino
Journal:  EMBO J       Date:  2001-04-02       Impact factor: 11.598

6.  Phosphorylation of type-1 inositol 1,4,5-trisphosphate receptors by cyclic nucleotide-dependent protein kinases: a mutational analysis of the functionally important sites in the S2+ and S2- splice variants.

Authors:  Larry E Wagner; Wen-Hong Li; David I Yule
Journal:  J Biol Chem       Date:  2003-08-25       Impact factor: 5.157

7.  Functional analysis of the green fluorescent protein-tagged inositol 1,4,5-trisphosphate receptor type 3 in Ca(2+) release and entry in DT40 B lymphocytes.

Authors:  Takao Morita; Akihiko Tanimura; Akihiro Nezu; Tomohiro Kurosaki; Yosuke Tojyo
Journal:  Biochem J       Date:  2004-09-15       Impact factor: 3.857

Review 8.  Inositol 1,4,5-trisphosphate receptors as signal integrators.

Authors:  Randen L Patterson; Darren Boehning; Solomon H Snyder
Journal:  Annu Rev Biochem       Date:  2004       Impact factor: 23.643

9.  Distinct roles of inositol 1,4,5-trisphosphate receptor types 1 and 3 in Ca2+ signaling.

Authors:  Mitsuharu Hattori; Akinobu Z Suzuki; Takayasu Higo; Hiroshi Miyauchi; Takayuki Michikawa; Takeshi Nakamura; Takafumi Inoue; Katsuhiko Mikoshiba
Journal:  J Biol Chem       Date:  2004-01-05       Impact factor: 5.157

10.  Agonist-induced Ca2+ entry determined by inositol 1,4,5-trisphosphate recognition.

Authors:  Damian B van Rossum; Randen L Patterson; Kirill Kiselyov; Darren Boehning; Roxanne K Barrow; Donald L Gill; Solomon H Snyder
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-24       Impact factor: 11.205
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  12 in total

1.  InsP3R-associated cGMP kinase substrate determines inositol 1,4,5-trisphosphate receptor susceptibility to phosphoregulation by cyclic nucleotide-dependent kinases.

Authors:  Wataru Masuda; Matthew J Betzenhauser; David I Yule
Journal:  J Biol Chem       Date:  2010-09-27       Impact factor: 5.157

2.  Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

Authors:  Kamil J Alzayady; Larry E Wagner; Rahul Chandrasekhar; Alina Monteagudo; Ronald Godiska; Gregory G Tall; Suresh K Joseph; David I Yule
Journal:  J Biol Chem       Date:  2013-08-16       Impact factor: 5.157

3.  Regulation of Ca²⁺ release through inositol 1,4,5-trisphosphate receptors by adenine nucleotides in parotid acinar cells.

Authors:  Hyung Seo Park; Matthew J Betzenhauser; Yu Zhang; David I Yule
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2011-09-29       Impact factor: 4.052

4.  Apoptosis protection by Mcl-1 and Bcl-2 modulation of inositol 1,4,5-trisphosphate receptor-dependent Ca2+ signaling.

Authors:  Emily F Eckenrode; Jun Yang; Gopal V Velmurugan; J Kevin Foskett; Carl White
Journal:  J Biol Chem       Date:  2010-02-26       Impact factor: 5.157

5.  Protein kinase A increases type-2 inositol 1,4,5-trisphosphate receptor activity by phosphorylation of serine 937.

Authors:  Matthew J Betzenhauser; Jenna L Fike; Larry E Wagner; David I Yule
Journal:  J Biol Chem       Date:  2009-07-16       Impact factor: 5.157

6.  Isoform- and species-specific control of inositol 1,4,5-trisphosphate (IP3) receptors by reactive oxygen species.

Authors:  Száva Bánsághi; Tünde Golenár; Muniswamy Madesh; György Csordás; Satish RamachandraRao; Kumar Sharma; David I Yule; Suresh K Joseph; György Hajnóczky
Journal:  J Biol Chem       Date:  2014-01-27       Impact factor: 5.157

7.  The BRCA1 tumor suppressor binds to inositol 1,4,5-trisphosphate receptors to stimulate apoptotic calcium release.

Authors:  Serena C Hedgepeth; M Iveth Garcia; Larry E Wagner; Ana M Rodriguez; Sree V Chintapalli; Russell R Snyder; Gary D V Hankins; Beric R Henderson; Kirsty M Brodie; David I Yule; Damian B van Rossum; Darren Boehning
Journal:  J Biol Chem       Date:  2015-02-02       Impact factor: 5.157

8.  Fragmented inositol 1,4,5-trisphosphate receptors retain tetrameric architecture and form functional Ca2+ release channels.

Authors:  Kamil J Alzayady; Rahul Chandrasekhar; David I Yule
Journal:  J Biol Chem       Date:  2013-03-11       Impact factor: 5.157

9.  ATP regulation of type-1 inositol 1,4,5-trisphosphate receptor activity does not require walker A-type ATP-binding motifs.

Authors:  Matthew J Betzenhauser; Larry E Wagner; Hyung Seo Park; David I Yule
Journal:  J Biol Chem       Date:  2009-04-22       Impact factor: 5.157

Review 10.  Ca(2+) channels on the move.

Authors:  Colin W Taylor; David L Prole; Taufiq Rahman
Journal:  Biochemistry       Date:  2009-12-29       Impact factor: 3.162
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