Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Gestational trophoblastic neoplasia: an update.

Literature DB >> 18928664

Gestational trophoblastic neoplasia: an update.

Abstract

Gestational trophoblastic neoplasia (GTN) includes invasive mole, choriocarcinoma, and placental site trophoblastic tumors. The overall cure rate in treating these tumors currently exceeds 90%. Thorough evaluation and staging allow selection of appropriate therapy that maximizes chances for cure while minimizing toxicity. Nonmetastatic (stage I) and low-risk metastatic (stages II and III, World Health Organization score < 7) GTN can be treated with single-agent chemotherapy, resulting in a survival rate approaching 100%. High-risk metastatic GTN (stage IV, WHO score > or = 7) requires initial multiagent chemotherapy with or without adjuvant radiation and surgery to achieve a survival rate of 80% to 90%.

Entities: Disease

Mesh：

Substances：

Year: 2008 PMID： 18928664 DOI： 10.1007/s11912-008-0075-y

Source DB: PubMed Journal: Curr Oncol Rep ISSN： 1523-3790 Impact factor: 5.075

49 in total

1. A single institution experience with weekly intramuscular methotrexate for nonmetastatic gestational trophoblastic disease.

Authors: M S Hoffman; J V Fiorica; N C Gleeson; W S Roberts; D Cavanagh
Journal: Gynecol Oncol Date: 1996-02 Impact factor: 5.482

2. Placental site trophoblastic tumor: A study of 55 cases and review of the literature emphasizing factors of prognostic significance.

Authors: Rebecca N Baergen; Joanne L Rutgers; Robert H Young; Kathryn Osann; Robert E Scully
Journal: Gynecol Oncol Date: 2005-10-21 Impact factor: 5.482

3. Treatment of low-risk metastatic gestational trophoblastic tumors with single-agent chemotherapy.

Authors: J P Roberts; J R Lurain
Journal: Am J Obstet Gynecol Date: 1996-06 Impact factor: 8.661

4. The management of gestational trophoblastic tumors with etoposide, methotrexate, and actinomycin D.

Authors: V Soto-Wright; D P Goldstein; M R Bernstein; R S Berkowitz
Journal: Gynecol Oncol Date: 1997-01 Impact factor: 5.482

5. Methotrexate infusion in low-risk gestational trophoblastic disease.

Authors: L C Wong; H Y Ngan; D K Cheng; T Y Ng
Journal: Am J Obstet Gynecol Date: 2000-12 Impact factor: 8.661

6. Relapsed gestational trophoblastic neoplasia: A 20-year experience.

Authors: Hextan Y S Ngan; Kar-Fai Tam; Ka-Wai Lam; Karen K L Chan
Journal: J Reprod Med Date: 2006-10 Impact factor: 0.142

7. The role of low-dose methotrexate and folinic acid in gestational trophoblastic tumours (GTT).

Authors: K D Bagshawe; J Dent; E S Newlands; R H Begent; G J Rustin
Journal: Br J Obstet Gynaecol Date: 1989-07

8. EMA-CO chemotherapy for high-risk gestational trophoblastic neoplasia: a clinical analysis of 54 patients.

Authors: W-G Lu; F Ye; Y-M Shen; Y-F Fu; H-Z Chen; X-Y Wan; X Xie
Journal: Int J Gynecol Cancer Date: 2007-08-17 Impact factor: 3.437

9. Results with the EMA/CO (etoposide, methotrexate, actinomycin D, cyclophosphamide, vincristine) regimen in high risk gestational trophoblastic tumours, 1979 to 1989.

Authors: E S Newlands; K D Bagshawe; R H Begent; G J Rustin; L Holden
Journal: Br J Obstet Gynaecol Date: 1991-06

Review 10. Weekly intramuscular methotrexate for nonmetastatic gestational trophoblastic disease.

Authors: H D Homesley; J A Blessing; M Rettenmaier; R L Capizzi; F J Major; L B Twiggs
Journal: Obstet Gynecol Date: 1988-09 Impact factor: 7.661

9 in total

1. Cost-effectiveness of second curettage for treatment of low-risk non-metastatic gestational trophoblastic neoplasia.

Authors: Samantha Batman; Ashley Skeith; Allison Allen; Elizabeth Munro; Aaron Caughey; Amanda Bruegl
Journal: Gynecol Oncol Date: 2020-04-08 Impact factor: 5.482

2. Choriocarcinoma with multiple lung, skull and skin metastases in a postmenopausal female: A case report.

Authors: Xiao-Man Li; Xiao-Yun Liu; Zhi-Xia Liu
Journal: Oncol Lett Date: 2015-09-25 Impact factor: 2.967

3. FIGO stage IV gestational choriocarcinoma misdiagnosed as pulmonary tuberculosis: A case report.

Authors: Lingyun Yang; Pang Xu; Mingrong Xi; Hongjing Wang
Journal: Oncol Lett Date: 2015-07-01 Impact factor: 2.967

Review 4. Genotyping diagnosis of gestational trophoblastic disease: frontiers in precision medicine.

Authors: Natalia Buza; Pei Hui
Journal: Mod Pathol Date: 2021-06-04 Impact factor: 7.842

5. LPCAT1-TERT fusions are uniquely recurrent in epithelioid trophoblastic tumors and positively regulate cell growth.

Authors: Gavin R Oliver; Sofia Marcano-Bonilla; Jonathan Quist; Ezequiel J Tolosa; Eriko Iguchi; Amy A Swanson; Nicole L Hoppman; Tanya Schwab; Ashley Sigafoos; Naresh Prodduturi; Jesse S Voss; Shannon M Knight; Jin Zhang; Numrah Fadra; Raul Urrutia; Michael Zimmerman; Jan B Egan; Anthony G Bilyeu; Jin Jen; Ema Veras; Rema'a Al-Safi; Matthew Block; Sarah Kerr; Martin E Fernandez-Zapico; John K Schoolmeester; Eric W Klee
Journal: PLoS One Date: 2021-05-25 Impact factor: 3.240

6. Doppler-based predictive model for methotrexate resistance in low-risk gestational trophoblastic neoplasia with myometrial invasion: prospective study of 147 patients.

Authors: J Qin; S Zhang; L Poon; Z Pan; J Luo; N Yu; L Wang; X Wu; X Cheng; X Xie; Y Lu; W Lu
Journal: Ultrasound Obstet Gynecol Date: 2021-05 Impact factor: 7.299