Literature DB >> 18923072

Histone H2B ubiquitination: the cancer connection.

Joaquín M Espinosa1.   

Abstract

Post-translational modifications of histones play a critical role in gene expression control. Ultimately, cancer is a disease of aberrant gene expression. Accordingly, several histone-modifying enzymes have been described as proto-oncogenes or tumor suppressors. Recent reports, including one from Shema and colleagues (pp. 2664- 2676) in the October 1, 2008, issue of Genes and Development, indicate that deregulation of histone H2B monoubiquitination may contribute to cancer development.

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Year:  2008        PMID： 18923072      PMCID： PMC2751279          DOI： 10.1101/gad.1732108

Source DB:  PubMed          Journal:  Genes Dev        ISSN： 0890-9369            Impact factor:   11.361


  46 in total

1.  The RING domain of Mdm2 mediates histone ubiquitylation and transcriptional repression.

Authors:  Neri Minsky; Moshe Oren
Journal:  Mol Cell       Date:  2004-11-19       Impact factor: 17.970

2.  The disruption of ND10 during herpes simplex virus infection correlates with the Vmw110- and proteasome-dependent loss of several PML isoforms.

Authors:  R D Everett; P Freemont; H Saitoh; M Dasso; A Orr; M Kathoria; J Parkinson
Journal:  J Virol       Date:  1998-08       Impact factor: 5.103

3.  Maintenance of low histone ubiquitylation by Ubp10 correlates with telomere-proximal Sir2 association and gene silencing.

Authors:  N C Tolga Emre; Kristin Ingvarsdottir; Anastasia Wyce; Adam Wood; Nevan J Krogan; Karl W Henry; Keqin Li; Ronen Marmorstein; Jack F Greenblatt; Ali Shilatifard; Shelley L Berger
Journal:  Mol Cell       Date:  2005-02-18       Impact factor: 17.970

4.  The chromatin-specific transcription elongation factor FACT comprises human SPT16 and SSRP1 proteins.

Authors:  G Orphanides; W H Wu; W S Lane; M Hampsey; D Reinberg
Journal:  Nature       Date:  1999-07-15       Impact factor: 49.962

5.  Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.

Authors:  M H Koken; P Reynolds; I Jaspers-Dekker; L Prakash; S Prakash; D Bootsma; J H Hoeijmakers
Journal:  Proc Natl Acad Sci U S A       Date:  1991-10-15       Impact factor: 11.205

6.  Histone H2B ubiquitylation is associated with elongating RNA polymerase II.

Authors:  Tiaojiang Xiao; Cheng-Fu Kao; Nevan J Krogan; Zu-Wen Sun; Jack F Greenblatt; Mary Ann Osley; Brian D Strahl
Journal:  Mol Cell Biol       Date:  2005-01       Impact factor: 4.272

7.  GMP synthetase stimulates histone H2B deubiquitylation by the epigenetic silencer USP7.

Authors:  Jan A van der Knaap; B R Prashanth Kumar; Yuri M Moshkin; Karin Langenberg; Jeroen Krijgsveld; Albert J R Heck; François Karch; C Peter Verrijzer
Journal:  Mol Cell       Date:  2005-03-04       Impact factor: 17.970

8.  The histone H2B-specific ubiquitin ligase RNF20/hBRE1 acts as a putative tumor suppressor through selective regulation of gene expression.

Authors:  Efrat Shema; Itay Tirosh; Yael Aylon; Jing Huang; Chaoyang Ye; Neta Moskovits; Nina Raver-Shapira; Neri Minsky; Judith Pirngruber; Gabi Tarcic; Pavla Hublarova; Lilach Moyal; Mali Gana-Weisz; Yosef Shiloh; Yossef Yarden; Steven A Johnsen; Borivoj Vojtesek; Shelley L Berger; Moshe Oren
Journal:  Genes Dev       Date:  2008-10-01       Impact factor: 11.361

9.  Inactivation of the HR6B ubiquitin-conjugating DNA repair enzyme in mice causes male sterility associated with chromatin modification.

Authors:  H P Roest; J van Klaveren; J de Wit; C G van Gurp; M H Koken; M Vermey; J H van Roijen; J W Hoogerbrugge; J T Vreeburg; W M Baarends; D Bootsma; J A Grootegoed; J H Hoeijmakers
Journal:  Cell       Date:  1996-09-06       Impact factor: 41.582

10.  Evidence for eviction and rapid deposition of histones upon transcriptional elongation by RNA polymerase II.

Authors:  Marc A Schwabish; Kevin Struhl
Journal:  Mol Cell Biol       Date:  2004-12       Impact factor: 4.272
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  27 in total

Review 1.  Histone H2B ubiquitination and beyond: Regulation of nucleosome stability, chromatin dynamics and the trans-histone H3 methylation.

Authors:  Mahesh B Chandrasekharan; Fu Huang; Zu-Wen Sun
Journal:  Epigenetics       Date:  2010-08-16       Impact factor: 4.528

2.  Regulation of histone H2A and H2B deubiquitination and Xenopus development by USP12 and USP46.

Authors:  Heui-Yun Joo; Amada Jones; Chunying Yang; Ling Zhai; Archer D Smith; Zhuo Zhang; Mahesh B Chandrasekharan; Zu-wen Sun; Matthew B Renfrow; Yanming Wang; Chenbei Chang; Hengbin Wang
Journal:  J Biol Chem       Date:  2010-12-23       Impact factor: 5.157

Review 3.  Flickin' the ubiquitin switch: the role of H2B ubiquitylation in development.

Authors:  Duncan Edward Wright; Chen-Yi Wang; Cheng-Fu Kao
Journal:  Epigenetics       Date:  2011-10-01       Impact factor: 4.528

4.  Chemo-Genetic Interactions Between Histone Modification and the Antiproliferation Drug AICAR Are Conserved in Yeast and Humans.

Authors:  Delphine Albrecht; Johanna Ceschin; Jim Dompierre; Florian Gueniot; Benoît Pinson; Bertrand Daignan-Fornier
Journal:  Genetics       Date:  2016-10-05       Impact factor: 4.562

5.  Biosynthetic enzyme GMP synthetase cooperates with ubiquitin-specific protease 7 in transcriptional regulation of ecdysteroid target genes.

Authors:  Jan A van der Knaap; Elena Kozhevnikova; Karin Langenberg; Yuri M Moshkin; C Peter Verrijzer
Journal:  Mol Cell Biol       Date:  2009-12-07       Impact factor: 4.272

6.  MUSIC: identification of enriched regions in ChIP-Seq experiments using a mappability-corrected multiscale signal processing framework.

Authors:  Arif Harmanci; Joel Rozowsky; Mark Gerstein
Journal:  Genome Biol       Date:  2014       Impact factor: 13.583

Review 7.  Purification of histone ubiquitin ligases from HeLa cells.

Authors:  Amanda Jones; Heui-Yun Joo; Woody Robbins; Hengbin Wang
Journal:  Methods       Date:  2011-03-21       Impact factor: 3.608

8.  RNF20 inhibits TFIIS-facilitated transcriptional elongation to suppress pro-oncogenic gene expression.

Authors:  Efrat Shema; Jaehoon Kim; Robert G Roeder; Moshe Oren
Journal:  Mol Cell       Date:  2011-05-20       Impact factor: 17.970

9.  Rad6 upregulation promotes stem cell-like characteristics and platinum resistance in ovarian cancer.

Authors:  Ranganatha R Somasagara; Kaushlendra Tripathi; Sebastian M Spencer; David W Clark; Reagan Barnett; Lavanya Bachaboina; Jennifer Scalici; Rodney P Rocconi; Gary A Piazza; Komaraiah Palle
Journal:  Biochem Biophys Res Commun       Date:  2015-12-08       Impact factor: 3.575

10.  Decreased histone H2B monoubiquitination in malignant gastric carcinoma.

Authors:  Zi-Jing Wang; Jing-Lin Yang; Yi-Ping Wang; Jiang-Yan Lou; Jie Chen; Cong Liu; Lian-Di Guo
Journal:  World J Gastroenterol       Date:  2013-11-28       Impact factor: 5.742
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