Literature DB >> 18922003

Relative and absolute stereochemistry of quinadoline B, an inhibitor of lipid droplet synthesis in macrophages.

Nobuhiro Koyama1, Yusuke Inoue, Masae Sekine, Yoichi Hayakawa, Hiroshi Homma, Satoshi Omura, Hiroshi Tomoda.   

Abstract

New fungal metabolites, designated quinadolines A (1) and B (2), were isolated from culture broth of Aspergillus sp. FKI-1746, and their structures were elucidated by NMR spectroscopy. The complete relative and absolute stereochemistry of 2 was determined by X-ray crystallography and amino acid analysis using a chiral column. Quinadolines moderately inhibited lipid droplet synthesis in mouse macrophages.

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Year:  2008        PMID: 18922003     DOI: 10.1021/ol802089p

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  7 in total

1.  Tryptoquivalines W and X, two new compounds from a Hawaiian fungal strain and their biological activities.

Authors:  Kh Ahammad Uz Zaman; Zhenquan Hu; Xiaohua Wu; Shugeng Cao
Journal:  Tetrahedron Lett       Date:  2020-02-11       Impact factor: 2.415

2.  Hexafluoroisopropyl alcohol mediated synthesis of 2,3-dihydro-4H-pyrido[1,2-a]pyrimidin-4-ones.

Authors:  Mohammad A Alam; Zakeyah Alsharif; Hessa Alkhattabi; Derika Jones; Evan Delancey; Adam Gottsponer; Tianhong Yang
Journal:  Sci Rep       Date:  2016-11-02       Impact factor: 4.379

3.  Polyketides and Alkaloids from the Marine-Derived Fungus Dichotomomyces cejpii F31-1 and the Antiviral Activity of Scequinadoline A against Dengue Virus.

Authors:  Dong-Lan Wu; Hou-Jin Li; Duncan R Smith; Janejira Jaratsittisin; Xia-Fu-Kai-Ti Xia-Ke-Er; Wen-Zhe Ma; Yong-Wei Guo; Jun Dong; Juan Shen; De-Po Yang; Wen-Jian Lan
Journal:  Mar Drugs       Date:  2018-07-06       Impact factor: 5.118

Review 4.  Natural Products for the Prevention and Control of the COVID-19 Pandemic: Sustainable Bioresources.

Authors:  Rajeev K Singla; Xuefei He; Hitesh Chopra; Christos Tsagkaris; Li Shen; Mohammad Amjad Kamal; Bairong Shen
Journal:  Front Pharmacol       Date:  2021-12-01       Impact factor: 5.810

5.  A Mixture of Atropisomers Enhances Neutral Lipid Degradation in Mammalian Cells with Autophagy Induction.

Authors:  Keisuke Kobayashi; Satoshi Ohte; Taichi Ohshiro; Narihiro Ugaki; Hiroshi Tomoda
Journal:  Sci Rep       Date:  2018-08-14       Impact factor: 4.379

6.  Highly Oxygenated Constituents from a Marine Alga-Derived Fungus Aspergillus giganteus NTU967.

Authors:  Jih-Jung Chen; Shih-Wei Wang; Yin-Ru Chiang; Ka-Lai Pang; Yueh-Hsiung Kuo; Tsai-Yen Shih; Tzong-Huei Lee
Journal:  Mar Drugs       Date:  2020-06-06       Impact factor: 5.118

7.  Three New Quinazoline-Containing Indole Alkaloids From the Marine-Derived Fungus Aspergillus sp. HNMF114.

Authors:  Sha-Sha Liu; Li Yang; Fan-Dong Kong; Jia-Hui Zhao; Li Yao; Zhi-Guang Yuchi; Qing-Yun Ma; Qing-Yi Xie; Li-Man Zhou; Meng-Fei Guo; Hao-Fu Dai; You-Xing Zhao; Du-Qiang Luo
Journal:  Front Microbiol       Date:  2021-06-02       Impact factor: 5.640

  7 in total

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