Literature DB >> 18855157

RapidArc volumetric modulated therapy planning for prostate cancer patients.

Flemming Kjaer-Kristoffersen1, Lars Ohlhues, Joakim Medin, Stine Korreman.   

Abstract

PURPOSE: Recently, Varian Medical Systems have announced the introduction of a new treatment technique, RapidArc, in which dose is delivered over a single gantry rotation with dynamically variable MLC positions, dose rate and gantry speed. At Rigshospitalet, the RapidArc technique was brought into clinical practice in May 2008 for treatment of prostate cancer patients. We report here our experiences with performing treatment planning using the Eclipse RapidArc optimization software for this patient group.
MATERIAL AND METHODS: A stand-alone installation of Eclipse 8.5 with RapidArc optimization capability was performed at Rigshospitalet. Patient data for 8 prostate cancer patients were imported, most of whom were previously treated at Rigshospitalet using IMRT. Three of the patients were treated at Rigshospitalet using the RapidArc technique. Treatment plans were optimized using objectives as given by standard guidelines for clinical treatment planning. RapidArc plans were compared to the IMRT plans by which the patients were actually treated or in the three cases treated with the RapidArc technique to IMRT plans achieved using standard guidelines. Comparison was done with respect to target coverage, doses to rectum and bladder, over-all maximum dose and number of monitor units.
RESULTS: Overall, the RapidArc treatment plans gave better or equal sparing of the organs at risk than the IMRT treatment plans. The number of monitor units was lower in most cases, by up to approximately 75%. However, the target dose homogeneity was not as high as for IMRT. The low-dose bath was larger than for IMRT.
CONCLUSION: RapidArc optimization is very promising, especially regarding the potential of reducing the number of monitor units, while providing good sparing of organs at risk. Some improvement is still warranted with respect to achieving high target dose homogeneity.

Entities:  

Mesh:

Year:  2009        PMID: 18855157     DOI: 10.1080/02841860802266748

Source DB:  PubMed          Journal:  Acta Oncol        ISSN: 0284-186X            Impact factor:   4.089


  49 in total

Review 1.  Volumetric modulated arc therapy: a review of current literature and clinical use in practice.

Authors:  M Teoh; C H Clark; K Wood; S Whitaker; A Nisbet
Journal:  Br J Radiol       Date:  2011-11       Impact factor: 3.039

Review 2.  Technological advances in radiation therapy for prostate cancer.

Authors:  Mehee Choi; Arthur Y Hung
Journal:  Curr Urol Rep       Date:  2010-05       Impact factor: 3.092

3.  A dosimetric comparison of RapidArc and IMRT with hypofractionated simultaneous integrated boost to the prostate for treatment of prostate cancer.

Authors:  K Ishii; R Ogino; W Okada; R Nakahara; R Kawamorita; T Nakajima
Journal:  Br J Radiol       Date:  2013-08-30       Impact factor: 3.039

4.  Single-arc volumetric-modulated arc therapy can provide dose distributions equivalent to fixed-beam intensity-modulated radiation therapy for prostatic irradiation with seminal vesicle and/or lymph node involvement.

Authors:  J D Fontenot; M L King; S A Johnson; C G Wood; M J Price; K K Lo
Journal:  Br J Radiol       Date:  2011-06-28       Impact factor: 3.039

5.  Calculating and estimating second cancer risk from breast radiotherapy using Monte Carlo code with internal body scatter for each out-of-field organ.

Authors:  Takeshi Takata; Kenshiro Shiraishi; Shinobu Kumagai; Norikazu Arai; Takenori Kobayashi; Hiroshi Oba; Takahide Okamoto; Jun'ichi Kotoku
Journal:  J Appl Clin Med Phys       Date:  2020-10-30       Impact factor: 2.102

6.  Outcome and toxicity profiles in the treatment of locally advanced lung cancer with volumetric modulated arc therapy.

Authors:  Marta Scorsetti; Piera Navarria; Fiorenza De Rose; AnnaMaria Ascolese; Elena Clerici; Ciro Franzese; Francesca Lobefalo; Giacomo Reggiori; Pietro Mancosu; Stefano Tomatis; Antonella Fogliata; Luca Cozzi
Journal:  J Cancer Res Clin Oncol       Date:  2014-06-17       Impact factor: 4.553

7.  Neo-adjuvant chemo-radiation of rectal cancer with volumetric modulated arc therapy: summary of technical and dosimetric features and early clinical experience.

Authors:  Antonella Richetti; Antonella Fogliata; Alessandro Clivio; Giorgia Nicolini; Gianfranco Pesce; Emanuela Salati; Eugenio Vanetti; Luca Cozzi
Journal:  Radiat Oncol       Date:  2010-02-19       Impact factor: 3.481

8.  Application of volumetric modulated arc therapy (VMAT) in a dual-vendor environment.

Authors:  Barbara Dobler; Karin Weidner; Oliver Koelbl
Journal:  Radiat Oncol       Date:  2010-10-25       Impact factor: 3.481

9.  Whole abdomen radiation therapy in ovarian cancers: a comparison between fixed beam and volumetric arc based intensity modulation.

Authors:  Umesh Mahantshetty; Swamidas Jamema; Reena Engineer; Deepak Deshpande; Rajiv Sarin; Antonella Fogliata; Giorgia Nicolini; Alessandro Clivio; Eugenio Vanetti; Shyamkishore Shrivastava; Luca Cozzi
Journal:  Radiat Oncol       Date:  2010-11-15       Impact factor: 3.481

10.  Simultaneous integrated boost radiotherapy for bilateral breast: a treatment planning and dosimetric comparison for volumetric modulated arc and fixed field intensity modulated therapy.

Authors:  Giorgia Nicolini; Alessandro Clivio; Antonella Fogliata; Eugenio Vanetti; Luca Cozzi
Journal:  Radiat Oncol       Date:  2009-07-24       Impact factor: 3.481

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