Literature DB >> 1885485

Continuous infusion of high doses of atropine in the management of organophosphorus compound poisoning.

J S Ram1, S S Kumar, A Jayarajan, G Kuppuswamy.   

Abstract

Forty five cases of organophosphorus poisoning were studied to evaluate the results of continuous infusion of high doses of atropine as against the conventional intermittent therapy. A statistically significant reduction in mortality (23.5% to 8.8%; p less than 0.05) was evident in this study as compared to previous years. Pseudocholinesterase levels below 10% of normal were associated with a poor prognosis and increased mortality.

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Year:  1991        PMID: 1885485

Source DB:  PubMed          Journal:  J Assoc Physicians India        ISSN: 0004-5772


  8 in total

1.  Prognostic significance of estimation of pseudocholinesterase activity and role of pralidoxime therapy in organophosphorous poisoning.

Authors:  Shyam Chand Chaudhary; Khemraj Singh; Kamal Kumar Sawlani; Nirdesh Jain; Arvind Kumar Vaish; Virendra Atam; Munna Lal Patel; Avinash Agarwal
Journal:  Toxicol Int       Date:  2013-09

2.  ORGANOPHOSPHOROUS POISONING WITH INTERMEDIATE SYNDROME.

Authors:  S Piplani; A Handa; R Aggrawal; B K Gupta; S C Mishra; P Roy; I D Gupta
Journal:  Med J Armed Forces India       Date:  2011-07-21

3.  The need for translational research on antidotes for pesticide poisoning.

Authors:  Nick A Buckley; Michael Eddleston; Andrew H Dawson
Journal:  Clin Exp Pharmacol Physiol       Date:  2005-11       Impact factor: 2.557

4.  Open-label randomized clinical trial of atropine bolus injection versus incremental boluses plus infusion for organophosphate poisoning in Bangladesh.

Authors:  Mohammed Joynal Abedin; Abdullah Abu Sayeed; Ariful Basher; Richard J Maude; Gofranul Hoque; M A Faiz
Journal:  J Med Toxicol       Date:  2012-06

5.  Speed of initial atropinisation in significant organophosphorus pesticide poisoning--a systematic comparison of recommended regimens.

Authors:  Michael Eddleston; Nick A Buckley; Helaina Checketts; Lalith Senarathna; Fahim Mohamed; M H Rezvi Sheriff; Andrew Dawson
Journal:  J Toxicol Clin Toxicol       Date:  2004

Review 6.  Antidotes for childhood toxidromes.

Authors:  Kam Lun Hon; Wun Fung Hui; Alexander Kc Leung
Journal:  Drugs Context       Date:  2021-06-02

7.  Patterns of poisoning and drug overdosage and their outcome among in-patients admitted to the emergency medicine department of a tertiary care hospital.

Authors:  Leena Anthony; Chanda Kulkarni
Journal:  Indian J Crit Care Med       Date:  2012-07

Review 8.  Management of acute organophosphorus pesticide poisoning.

Authors:  Michael Eddleston; Nick A Buckley; Peter Eyer; Andrew H Dawson
Journal:  Lancet       Date:  2008-02-16       Impact factor: 79.321

  8 in total

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