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Literature DB >> 18850197

The role of microenvironment in tumor angiogenesis.

Abstract

Tumor microenvironment is essential for tumor cell proliferation, angiogenesis, invasion and metastasis through its provision of survival signals, secretion of growth and pro-angiogenic factors, and direct adhesion molecule interactions. This review examines its importance in the induction of an angiogenic response in tumors and in multiple myeloma. The encouraging results of pre-clinical and clinical trials in which tumors have been treated by targeting the tumor microenvironment are also discussed.

Entities: Disease

Year: 2008 PMID： 18850197 PMCID： PMC2311496 DOI： 10.1007/s12263-008-0076-3

Source DB: PubMed Journal: Genes Nutr ISSN： 1555-8932 Impact factor: 5.523

65 in total

1. Insulin-like growth factor I is a dual effector of multiple myeloma cell growth.

Authors: N L Ge; S Rudikoff
Journal: Blood Date: 2000-10-15 Impact factor: 22.113

2. Bone marrow angiogenesis and progression in multiple myeloma.

Authors: A Vacca; D Ribatti; L Roncali; G Ranieri; G Serio; F Silvestris; F Dammacco
Journal: Br J Haematol Date: 1994-07 Impact factor: 6.998

3. Expression of organ-specific antigens on capillary endothelial cells.

Authors: R Auerbach; L Alby; L W Morrissey; M Tu; J Joseph
Journal: Microvasc Res Date: 1985-05 Impact factor: 3.514

4. CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma.

Authors: Suzanne Trudel; Zhi Hua Li; Ellen Wei; Marion Wiesmann; Hong Chang; Christine Chen; Donna Reece; Carla Heise; A Keith Stewart
Journal: Blood Date: 2004-12-14 Impact factor: 22.113

Review 5. Novel targeted drugs for the treatment of multiple myeloma: from bench to bedside.

Authors: B Bruno; L Giaccone; M Rotta; K Anderson; M Boccadoro
Journal: Leukemia Date: 2005-10 Impact factor: 11.528

6. CD45 expression by bone marrow plasma cells in multiple myeloma: clinical and biological correlations.

Authors: S Kumar; S V Rajkumar; T Kimlinger; P R Greipp; T E Witzig
Journal: Leukemia Date: 2005-08 Impact factor: 11.528

Review 7. The history of the angiogenic switch concept.

Authors: D Ribatti; B Nico; E Crivellato; A M Roccaro; A Vacca
Journal: Leukemia Date: 2006-09-21 Impact factor: 11.528

8. Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma.

Authors: B Dankbar; T Padró; R Leo; B Feldmann; M Kropff; R M Mesters; H Serve; W E Berdel; J Kienast
Journal: Blood Date: 2000-04-15 Impact factor: 22.113

9. A paracrine loop in the vascular endothelial growth factor pathway triggers tumor angiogenesis and growth in multiple myeloma.

Authors: Angelo Vacca; Roberto Ria; Domenico Ribatti; Fabrizio Semeraro; Valentin Djonov; Francesco Di Raimondo; Franco Dammacco
Journal: Haematologica Date: 2003-02 Impact factor: 9.941

Review 10. Carbohydrate structure in tumor immunity.

Authors: C L Reading; J T Hutchins
Journal: Cancer Metastasis Rev Date: 1985 Impact factor: 9.264

19 in total

Review 1. Identify multiple myeloma stem cells: Utopia?

Authors: Ilaria Saltarella; Aurelia Lamanuzzi; Antonia Reale; Angelo Vacca; Roberto Ria
Journal: World J Stem Cells Date: 2015-01-26 Impact factor: 5.326

2. Krüppel-like factor 8 overexpression is correlated with angiogenesis and poor prognosis in gastric cancer.

Authors: Wen-Fei Wang; Juan Li; Lu-Tao Du; Li-Li Wang; Yong-Mei Yang; Yi-Min Liu; Hui Liu; Xin Zhang; Zhao-Gang Dong; Gui-Xi Zheng; Chuan-Xin Wang
Journal: World J Gastroenterol Date: 2013-07-21 Impact factor: 5.742

3. Insulin promotes proliferative vitality and invasive capability of pancreatic cancer cells via hypoxia-inducible factor 1alpha pathway.

Authors: Li Wang; Wei Zhou; Shanmiao Gou; Tongling Wang; Tao Liu; Chunyou Wang
Journal: J Huazhong Univ Sci Technolog Med Sci Date: 2010-06-17

The role of microenvironment in tumor angiogenesis.

1. Insulin-like growth factor I is a dual effector of multiple myeloma cell growth.

2. Bone marrow angiogenesis and progression in multiple myeloma.

3. Expression of organ-specific antigens on capillary endothelial cells.

4. CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4;14) multiple myeloma.

Review 5. Novel targeted drugs for the treatment of multiple myeloma: from bench to bedside.

6. CD45 expression by bone marrow plasma cells in multiple myeloma: clinical and biological correlations.

Review 7. The history of the angiogenic switch concept.

8. Vascular endothelial growth factor and interleukin-6 in paracrine tumor-stromal cell interactions in multiple myeloma.

9. A paracrine loop in the vascular endothelial growth factor pathway triggers tumor angiogenesis and growth in multiple myeloma.

Review 10. Carbohydrate structure in tumor immunity.

Review 1. Identify multiple myeloma stem cells: Utopia?

2. Krüppel-like factor 8 overexpression is correlated with angiogenesis and poor prognosis in gastric cancer.

3. Insulin promotes proliferative vitality and invasive capability of pancreatic cancer cells via hypoxia-inducible factor 1alpha pathway.

4. Syndecan-1 is required for robust growth, vascularization, and metastasis of myeloma tumors in vivo.

5. Overexpression of LAPTM4B is correlated with tumor angiogenesis and poor prognosis in non-small cell lung cancer.

6. Macrophages and mesenchymal stromal cells support survival and proliferation of multiple myeloma cells.

7. VEGF directly suppresses activation of T cells from ascites secondary to ovarian cancer via VEGF receptor type 2.

Review 8. Molecular targeting of liposomal nanoparticles to tumor microenvironment.

9. Selaginellatamariscina attenuates metastasis via Akt pathways in oral cancer cells.

10. Bmi-1 promotes glioma angiogenesis by activating NF-κB signaling.