Literature DB >> 18850174

Cholesterol: from feeding to gene regulation.

C Martini1, V Pallottini.   

Abstract

We present here a brief description of the path that cholesterol covers from its intestinal absorption to its effects exerted on gene regulation. In particular, the relationship between cholesterol and the protein complexes involved in the intricate gene regulation mechanism implicated in cholesterol homeostasis will be discussed. In addition, a new target role for the pharmacological interventions of one of these factors, the insulin-induced gene (Insig) protein, will be introduced.

Entities:  

Year:  2007        PMID： 18850174      PMCID： PMC2474947          DOI： 10.1007/s12263-007-0049-y

Source DB:  PubMed          Journal:  Genes Nutr        ISSN： 1555-8932            Impact factor:   5.523


  133 in total

1.  Different sterol regulatory element-binding protein-1 isoforms utilize distinct co-regulatory factors to activate the promoter for fatty acid synthase.

Authors:  M M Magaña; S H Koo; H C Towle; T F Osborne
Journal:  J Biol Chem       Date:  2000-02-18       Impact factor: 5.157

Review 2.  Sterol regulatory element-binding proteins (SREBPs): key regulators of nutritional homeostasis and insulin action.

Authors:  T F Osborne
Journal:  J Biol Chem       Date:  2000-10-20       Impact factor: 5.157

3.  Resistance to diet-induced hypercholesterolemia and gallstone formation in ACAT2-deficient mice.

Authors:  K K Buhman; M Accad; S Novak; R S Choi; J S Wong; R L Hamilton; S Turley; R V Farese
Journal:  Nat Med       Date:  2000-12       Impact factor: 53.440

Review 4.  ATP-binding cassette transporter A1: a cell cholesterol exporter that protects against cardiovascular disease.

Authors:  John F Oram; Jay W Heinecke
Journal:  Physiol Rev       Date:  2005-10       Impact factor: 37.312

5.  Lymphatic absorption of shellfish sterols and their effects on cholesterol absorption.

Authors:  G V Vahouny; W E Connor; T Roy; D S Lin; L L Gallo
Journal:  Am J Clin Nutr       Date:  1981-04       Impact factor: 7.045

6.  Dynamin is involved in endolysosomal cholesterol delivery to the endoplasmic reticulum: role in cholesterol homeostasis.

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7.  Cloning, human chromosomal assignment, and adipose and hepatic expression of the CL-6/INSIG1 gene.

Authors:  Y Peng; E J Schwarz; M A Lazar; A Genin; N B Spinner; R Taub
Journal:  Genomics       Date:  1997-08-01       Impact factor: 5.736

8.  Overexpression of sterol regulatory element-binding protein-1a in mouse adipose tissue produces adipocyte hypertrophy, increased fatty acid secretion, and fatty liver.

Authors:  Jay D Horton; Iichiro Shimomura; Shinji Ikemoto; Yuriy Bashmakov; Robert E Hammer
Journal:  J Biol Chem       Date:  2003-07-10       Impact factor: 5.157

Review 9.  Caveolin-1 as a potential new therapeutic target in multiple myeloma.

Authors:  Klaus Podar; Kenneth C Anderson
Journal:  Cancer Lett       Date:  2006-02-20       Impact factor: 8.679

10.  Gender-related differences in bile acid and sterol metabolism in outbred CD-1 mice fed low- and high-cholesterol diets.

Authors:  S D Turley; M Schwarz; D K Spady; J M Dietschy
Journal:  Hepatology       Date:  1998-10       Impact factor: 17.425
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  15 in total

Review 1.  Diabetes, Obesity, and Breast Cancer.

Authors:  Chifei Kang; Derek LeRoith; Emily J Gallagher
Journal:  Endocrinology       Date:  2018-11-01       Impact factor: 4.736

2.  Regulation and deregulation of cholesterol homeostasis: The liver as a metabolic "power station".

Authors:  Laura Trapani; Marco Segatto; Valentina Pallottini
Journal:  World J Hepatol       Date:  2012-06-27

Review 3.  Obesity and Diabetes: The Increased Risk of Cancer and Cancer-Related Mortality.

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Review 4.  Plenary Lecture 2: Transcription factors, regulatory elements and nutrient-gene communication.

Authors:  Robert J Cousins; Tolunay B Aydemir; Louis A Lichten
Journal:  Proc Nutr Soc       Date:  2009-12-08       Impact factor: 6.297

5.  Age-Related Hypercholesterolemia and HMG-CoA Reductase Dysregulation: Sex Does Matter (A Gender Perspective).

Authors:  Laura Trapani; Valentina Pallottini
Journal:  Curr Gerontol Geriatr Res       Date:  2010-05-04

6.  Isolated hypercholesterolemia leads to steatosis in the liver without affecting the pancreas.

Authors:  Csaba Csonka; Tamás Baranyai; László Tiszlavicz; Hedvig Fébel; Gergő Szűcs; Zoltán V Varga; Márta Sárközy; László G Puskás; Otilia Antal; Andrea Siska; Imre Földesi; Péter Ferdinandy; László Czakó; Tamás Csont
Journal:  Lipids Health Dis       Date:  2017-07-27       Impact factor: 3.876

Review 7.  Impact of Sex and Age on the Mevalonate Pathway in the Brain: A Focus on Effects Induced by Maternal Exposure to Exogenous Compounds.

Authors:  Claudia Tonini; Marco Segatto; Valentina Pallottini
Journal:  Metabolites       Date:  2020-07-25

8.  Effects of Late-Life Caloric Restriction on Age-Related Alterations in the Rat Cortex and Hippocampus.

Authors:  Claudia Tonini; Marco Segatto; Francesca Martino; Luisa Cigliano; Martina Nazzaro; Laura Barberio; Maurizio Mandalà; Valentina Pallottini
Journal:  Nutrients       Date:  2021-01-15       Impact factor: 5.717

Review 9.  Neurotrophins as Key Regulators of Cell Metabolism: Implications for Cholesterol Homeostasis.

Authors:  Mayra Colardo; Noemi Martella; Daniele Pensabene; Silvia Siteni; Sabrina Di Bartolomeo; Valentina Pallottini; Marco Segatto
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Review 10.  Long Non-Coding RNA Associated with Cholesterol Homeostasis and Its Involvement in Metabolic Diseases.

Authors:  Kang-Hoon Lee; Hyeon-Ji Hwang; Je-Yoel Cho
Journal:  Int J Mol Sci       Date:  2020-11-06       Impact factor: 5.923
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