Literature DB >> 18850035

Vertebral osteomyelitis: a potentially catastrophic outcome after lumbar epidural steroid injection.

Thomas T Simopoulos1, Jan J Kraemer, Paul Glazer, Zahid H Bajwa.   

Abstract

BACKGROUND AND
OBJECTIVE: Epidural steroid injections are commonly used to palliate the symptoms of spinal stenosis. Deep tissue infection is a known potential complication of these injections. There have been no previous published cases of osteomyelitis without epidural abscess after such injections. We present a case in an elderly patient who presented only with persistent axial low back pain following a lumbar epidural steroid injection (LESI). We emphasize early patient evaluation, consideration of infectious predisposing factors, sterile technique, and skin disinfectant.
DESIGN: Open-label case report. CASE DESCRIPTION: A 77-year-old diabetic male with a history of radicular pain related to lumbar spinal stenosis was treated successfully several years prior with a series of lumbar epidural steroid injections (LESI) and was re-treated with LESIs for recurrent symptoms. Following his second epidural injection, he presented with back pain and induration at the injection site without fever or neurological deficits. Urgent magnetic resonance imaging (MRI) revealed a soft tissue abscess extending close to the epidural space around the corresponding L4/L5 vertebral level. The patient recovered after incision and drainage of the abscess which was associated with an osteomyelitis of the L4 and L5 vertebral spine. The causative organism was methicillin-resistant Staphylococcus Aureus.
CONCLUSION: This case demonstrates that even with proper aseptic techniques, immune-compromised patients who are colonized with an aggressive micro-organism may develop a potentially catastrophic infectious complication if subtle persistent symptomatic complaints are not promptly and carefully evaluated.

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Year:  2008        PMID: 18850035

Source DB:  PubMed          Journal:  Pain Physician        ISSN: 1533-3159            Impact factor:   4.965


  9 in total

1.  Acute spinal cord compression due to epidural lipomatosis complicated by an abscess: magnetic resonance and pathology findings.

Authors:  Giulio Zuccoli; Nicolò Pipitone; Nicola De Carli; Luigi Vecchia; Stefano C Bartoletti
Journal:  Eur Spine J       Date:  2010-04-06       Impact factor: 3.134

2.  Exserohilum infections associated with contaminated steroid injections: a clinicopathologic review of 40 cases.

Authors:  Jana M Ritter; Atis Muehlenbachs; Dianna M Blau; Christopher D Paddock; Wun-Ju Shieh; Clifton P Drew; Brigid C Batten; Jeanine H Bartlett; Maureen G Metcalfe; Cau D Pham; Shawn R Lockhart; Mitesh Patel; Lindy Liu; Tara L Jones; Patricia W Greer; Jeltley L Montague; Elizabeth White; Dominique C Rollin; Cynthia Seales; Donna Stewart; Mark V Deming; Mary E Brandt; Sherif R Zaki
Journal:  Am J Pathol       Date:  2013-06-26       Impact factor: 4.307

3.  Epidural steroid injection-related events requiring hospitalisation or emergency room visits among 52,935 procedures performed at a single centre.

Authors:  Joon Woo Lee; Eugene Lee; Guen Young Lee; Yusuhn Kang; Joong Mo Ahn; Heung Sik Kang
Journal:  Eur Radiol       Date:  2017-07-19       Impact factor: 5.315

4.  Complications in image-guided musculoskeletal injections.

Authors:  John P Hynes; Meadhbh Ni Fhlatharta; James W Ryan; Peter J MacMahon; Stephen J Eustace; Eoin C Kavanagh
Journal:  Skeletal Radiol       Date:  2020-07-30       Impact factor: 2.199

Review 5.  Musculoskeletal Infections in the Emergency Department.

Authors:  Daniel C Kolinsky; Stephen Y Liang
Journal:  Emerg Med Clin North Am       Date:  2018-09-06       Impact factor: 2.264

Review 6.  Safety of Epidural Corticosteroid Injections.

Authors:  Ippokratis Pountos; Michalis Panteli; Gavin Walters; Dudley Bush; Peter V Giannoudis
Journal:  Drugs R D       Date:  2016-03

7.  Isolated oculomotor nerve palsy after lumbar epidural steroid injection in a diabetic patient.

Authors:  Yair M Gozal; Kristine Atchley; Bradford A Curt
Journal:  Surg Neurol Int       Date:  2016-12-26

8.  The Incidence of Various Types of Systemic Reactions Related to Epidural Steroid Injections: A Prospective Observational Study.

Authors:  Guen Young Lee; Joon Woo Lee; Jin S Yeom; Ki-Jeong Kim; Hyung-Ik Shin; Heung Sik Kang
Journal:  Korean J Radiol       Date:  2018-02-22       Impact factor: 3.500

9.  The Impact of Corticosteroid Injection Timing on Infection Rates Following Spine Surgery: A Systematic Review and Meta-Analysis.

Authors:  Gregory S Kazarian; Michael E Steinhaus; Han Jo Kim
Journal:  Global Spine J       Date:  2021-09-26
  9 in total

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