| Literature DB >> 18846469 |
Pawan Kumar Maurya1, Syed Ibrahim Rizvi.
Abstract
Antioxidant effect of tea catechins has been shown in many epidemiological studies. In the present study we report the protective mechanism of tea catechins (EGCG, ECG, EGC, EC) on various oxidative stress parameters, which are elevated during aging in humans. We hereby report the in vitro effect of tea catechins on erythrocyte malondialdehyde (MDA), reduced glutathione (GSH), and on membrane sulphydryl (-SH) group in humans. Results show an age-dependent increase in erythrocyte MDA level and a decrease in GSH and membrane-SH group concentration. We report that tea catechins show significant protection to erythrocyte against oxidative stress induced by tert-butyl hydroperoxide (t-BHP). The effect was more pronounced in older age group compared to lower age group. The findings suggest a possible role of tea catechins as anti-aging compounds.Entities:
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Year: 2009 PMID: 18846469 DOI: 10.1080/14786410802267643
Source DB: PubMed Journal: Nat Prod Res ISSN: 1478-6419 Impact factor: 2.861