Literature DB >> 18843523

How often is dizziness from primary cardiovascular disease true vertigo? A systematic review.

David E Newman-Toker1, Fei Jamie Dy, Victoria A Stanton, David S Zee, Hugh Calkins, Karen A Robinson.   

Abstract

OBJECTIVES: To assess how frequently cardiovascular dizziness is vertigo. Recent studies suggest providers do not consider cardiovascular causes when a patient reports true vertigo (spinning/motion) as opposed to presyncope (impending faint). It is known that cardiovascular disease causes dizziness, but unknown how often such dizziness is vertiginous, as opposed to presyncopal. DATA SOURCES: Systematic review of observational studies was made: Search--electronic (MEDLINE, EMBASE) and manual (references of eligible articles) search for English-language studies (1972-2007). REVIEW
METHODS: Inclusions Studies of >or=5 patients with confirmed cardiovascular causes for dizziness and reporting a proportion with vertigo were included. Two independent reviewers selected studies for inclusion, with differences adjudicated by a third. Study characteristics and dizziness-type proportions were abstracted. Studies were rated on methodology and quality of dizziness definitions. Differences were resolved by consensus.
RESULTS: We identified 1,506 citations, examined 125 full manuscripts, and included 5 studies. Principal reasons for exclusion were: abstracts--lack of original data, no cardiovascular diagnosis, or confounding exposure/disease (74%); manuscripts--failure to distinguish vertigo from other dizziness types (78%). In the three studies not using vertigo as an entry criterion (representing 1,659 patients with myocardial infarction, orthostatic hypotension, or syncope), vertigo was present in 63% (95% CI 57-69%) of cardiovascular patients with dizziness and the only dizziness type in 37% (95% CI 31-43%). Limitations include modest study quality and non-uniform definitions for vertigo.
CONCLUSIONS: Published data suggest that dizziness from primary cardiovascular disease may often be vertigo. Future research should assess prospectively whether dizziness type is a meaningful predictor for or against a cardiovascular diagnosis.

Entities:  

Mesh:

Year:  2008        PMID: 18843523      PMCID: PMC2596492          DOI: 10.1007/s11606-008-0801-z

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


  27 in total

1.  Do symptoms predict cardiac arrhythmias and mortality in patients with syncope?

Authors:  J H Oh; B H Hanusa; W N Kapoor
Journal:  Arch Intern Med       Date:  1999-02-22

2.  Painless aortic dissection with bilateral carotid involvement presenting with vertigo as the chief complaint.

Authors:  N S Demiryoguran; O Karcioglu; H Topacoglu; S Aksakalli
Journal:  Emerg Med J       Date:  2006-02       Impact factor: 2.740

3.  Charted records of dizzy patients suggest emergency physicians emphasize symptom quality in diagnostic assessment.

Authors:  David E Newman-Toker
Journal:  Ann Emerg Med       Date:  2007-08       Impact factor: 5.721

4.  Clinical research and geriatric dizziness: the blind men and the elephant.

Authors:  P D Sloane; J Dallara
Journal:  J Am Geriatr Soc       Date:  1999-01       Impact factor: 5.562

5.  A 69-year-old man with chronic dizziness.

Authors:  D A Drachman
Journal:  JAMA       Date:  1998 Dec 23-30       Impact factor: 56.272

6.  'Cardiogenic vertigo'--true vertigo as the presenting manifestation of primary cardiac disease.

Authors:  David E Newman-Toker; Carlos A Camargo
Journal:  Nat Clin Pract Neurol       Date:  2006-03

7.  The value of the clinical history in the differentiation of syncope due to ventricular tachycardia, atrioventricular block, and neurocardiogenic syncope.

Authors:  H Calkins; Y Shyr; H Frumin; A Schork; F Morady
Journal:  Am J Med       Date:  1995-04       Impact factor: 4.965

8.  Outcome in general medical patients presenting with common symptoms: a prospective study with a 2-week and a 3-month follow-up.

Authors:  K Kroenke; J L Jackson
Journal:  Fam Pract       Date:  1998-10       Impact factor: 2.267

9.  Overreliance on symptom quality in diagnosing dizziness: results of a multicenter survey of emergency physicians.

Authors:  Victoria A Stanton; Yu-Hsiang Hsieh; Carlos A Camargo; Jonathan A Edlow; Paris B Lovett; Paris Lovett; Joshua N Goldstein; Stephanie Abbuhl; Michelle Lin; Arjun Chanmugam; Richard E Rothman; David E Newman-Toker
Journal:  Mayo Clin Proc       Date:  2007-11       Impact factor: 7.616

10.  Prospective evaluation of clinical characteristics of orthostatic hypotension.

Authors:  P A Low; T L Opfer-Gehrking; B R McPhee; R D Fealey; E E Benarroch; C L Willner; G A Suarez; C J Proper; J A Felten; C A Huck
Journal:  Mayo Clin Proc       Date:  1995-07       Impact factor: 7.616

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  18 in total

Review 1.  [Syncope, falls and vertigo].

Authors:  C Weingart; H-J Schneider; C C Sieber
Journal:  Internist (Berl)       Date:  2017-09       Impact factor: 0.743

Review 2.  Recent advances in orthostatic hypotension presenting orthostatic dizziness or vertigo.

Authors:  Hyun-Ah Kim; Hyon-Ah Yi; Hyung Lee
Journal:  Neurol Sci       Date:  2015-08-21       Impact factor: 3.307

3.  Frequency, aetiology, and impact of vestibular symptoms in the emergency department: a neglected red flag.

Authors:  Martina Goeldlin; Janika Gaschen; Christoph Kammer; Lukas Comolli; Corrado A Bernasconi; Rainer Spiegel; Claudio L Bassetti; Aristomenis K Exadaktylos; Beat Lehmann; Georgios Mantokoudis; Roger Kalla; Urs Fischer
Journal:  J Neurol       Date:  2019-09-17       Impact factor: 4.849

4.  Does intracerebral haemorrhage mimic benign dizziness presentations? A population based study.

Authors:  Kevin A Kerber; James F Burke; Devin L Brown; William J Meurer; Melinda A Smith; Lynda D Lisabeth; Lewis B Morgenstern; Darin B Zahuranec
Journal:  Emerg Med J       Date:  2011-01-18       Impact factor: 2.740

5.  A New Diagnostic Approach to the Adult Patient with Acute Dizziness.

Authors:  Jonathan A Edlow; Kiersten L Gurley; David E Newman-Toker
Journal:  J Emerg Med       Date:  2018-02-01       Impact factor: 1.484

Review 6.  TiTrATE: A Novel, Evidence-Based Approach to Diagnosing Acute Dizziness and Vertigo.

Authors:  David E Newman-Toker; Jonathan A Edlow
Journal:  Neurol Clin       Date:  2015-08       Impact factor: 3.806

Review 7.  Diagnosing Stroke in Acute Dizziness and Vertigo: Pitfalls and Pearls.

Authors:  Ali S Saber Tehrani; Jorge C Kattah; Kevin A Kerber; Daniel R Gold; David S Zee; Victor C Urrutia; David E Newman-Toker
Journal:  Stroke       Date:  2018-02-19       Impact factor: 7.914

Review 8.  Betahistine for symptoms of vertigo.

Authors:  Louisa Murdin; Kiran Hussain; Anne G M Schilder
Journal:  Cochrane Database Syst Rev       Date:  2016-06-21

Review 9.  Medical and Nonstroke Neurologic Causes of Acute, Continuous Vestibular Symptoms.

Authors:  Jonathan A Edlow; David E Newman-Toker
Journal:  Neurol Clin       Date:  2015-08       Impact factor: 3.787

10.  The epidemiology of vertigo, dizziness, and unsteadiness and its links to co-morbidities.

Authors:  Alexandre Bisdorff; Gilles Bosser; René Gueguen; Philippe Perrin
Journal:  Front Neurol       Date:  2013-03-22       Impact factor: 4.003

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