Literature DB >> 18843382

Mitotic Origins of Chromosomal Instability in Colorectal Cancer.

W Brian Dalton, Vincent W Yang.   

Abstract

Mitosis is a crucial part of the cell cycle. A successful mitosis requires the proper execution of many complex cellular behaviors. Thus, there are many points at which mitosis may be disrupted. In cancer cells, chronic disruption of mitosis can lead to unequal segregation of chromosomes, a phenomenon known as chromosomal instability. A majority of colorectal tumors suffer from this instability, and recent studies have begun to reveal the specific ways in which mitotic defects promote chromosomal instability in colorectal cancer.

Entities:  

Year:  2007        PMID： 18843382      PMCID： PMC2562731          DOI： 10.1007/s11888-007-0001-y

Source DB:  PubMed          Journal:  Curr Colorectal Cancer Rep        ISSN： 1556-3790


  48 in total

Review 1.  Chromosome segregation and cancer: cutting through the mystery.

Authors:  P V Jallepalli; C Lengauer
Journal:  Nat Rev Cancer       Date:  2001-11       Impact factor: 60.716

2.  G(1) and G(2) cell-cycle arrest following microtubule depolymerization in human breast cancer cells.

Authors:  April L Blajeski; Vy A Phan; Timothy J Kottke; Scott H Kaufmann
Journal:  J Clin Invest       Date:  2002-07       Impact factor: 14.808

3.  Misorientation and reduced stretching of aligned sister kinetochores promote chromosome missegregation in EB1- or APC-depleted cells.

Authors:  V M Draviam; I Shapiro; B Aldridge; P K Sorger
Journal:  EMBO J       Date:  2006-06-08       Impact factor: 11.598

4.  Cell biology: nondisjunction, aneuploidy and tetraploidy.

Authors:  Beth A A Weaver; Alain D Silk; Don W Cleveland
Journal:  Nature       Date:  2006-08-17       Impact factor: 49.962

5.  Genetic and epigenetic inactivation of mitotic checkpoint genes hBUB1 and hBUBR1 and their relationship to survival.

Authors:  Masayoshi Shichiri; Keigo Yoshinaga; Hisashi Hisatomi; Kenichi Sugihara; Yukio Hirata
Journal:  Cancer Res       Date:  2002-01-01       Impact factor: 12.701

6.  Aneuploid colon cancer cells have a robust spindle checkpoint.

Authors:  A Tighe; V L Johnson; M Albertella; S S Taylor
Journal:  EMBO Rep       Date:  2001-07-03       Impact factor: 8.807

7.  Truncating APC mutations have dominant effects on proliferation, spindle checkpoint control, survival and chromosome stability.

Authors:  Anthony Tighe; Victoria L Johnson; Stephen S Taylor
Journal:  J Cell Sci       Date:  2004-11-23       Impact factor: 5.285

Review 8.  The significance of unstable chromosomes in colorectal cancer.

Authors:  Harith Rajagopalan; Martin A Nowak; Bert Vogelstein; Christoph Lengauer
Journal:  Nat Rev Cancer       Date:  2003-09       Impact factor: 60.716

9.  Rae1 is an essential mitotic checkpoint regulator that cooperates with Bub3 to prevent chromosome missegregation.

Authors:  J Ramesh Babu; Karthik B Jeganathan; Darren J Baker; Xiaosheng Wu; Ningling Kang-Decker; Jan M van Deursen
Journal:  J Cell Biol       Date:  2003-01-27       Impact factor: 10.539

10.  Mutational inactivation of mitotic checkpoint genes, hsMAD2 and hBUB1, is rare in sporadic digestive tract cancers.

Authors:  Y Imai; Y Shiratori; N Kato; T Inoue; M Omata
Journal:  Jpn J Cancer Res       Date:  1999-08
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  7 in total

Review 1.  DNA damage response pathways and cell cycle checkpoints in colorectal cancer: current concepts and future perspectives for targeted treatment.

Authors:  S Solier; Y-W Zhang; A Ballestrero; Y Pommier; G Zoppoli
Journal:  Curr Cancer Drug Targets       Date:  2012-05       Impact factor: 3.428

Review 2.  Role of prolonged mitotic checkpoint activation in the formation and treatment of cancer.

Authors:  W Brian Dalton; Vincent W Yang
Journal:  Future Oncol       Date:  2009-11       Impact factor: 3.404

3.  Human cancer cells commonly acquire DNA damage during mitotic arrest.

Authors:  W Brian Dalton; Mandayam O Nandan; Ryan T Moore; Vincent W Yang
Journal:  Cancer Res       Date:  2007-12-15       Impact factor: 12.701

4.  Molecular events in primary and metastatic colorectal carcinoma: a review.

Authors:  Rani Kanthan; Jenna-Lynn Senger; Selliah Chandra Kanthan
Journal:  Patholog Res Int       Date:  2012-05-09

Review 5.  Tumor suppressor genes in familial adenomatous polyposis.

Authors:  Nahal Eshghifar; Naser Farrokhi; Tahereh Naji; Mohammadreza Zali
Journal:  Gastroenterol Hepatol Bed Bench       Date:  2017

6.  Role of miRNAs in Sigmoid Colon Cancer: A Search for Potential Biomarkers.

Authors:  Diego Marques; Layse Raynara Ferreira-Costa; Lorenna Larissa Ferreira-Costa; Ana Beatriz Bezerra-Oliveira; Romualdo da Silva Correa; Carlos Cesar de Oliveira Ramos; Tatiana Vinasco-Sandoval; Katia de Paiva Lopes; Ricardo Assunção Vialle; Amanda Ferreira Vidal; Vivian Nogueira Silbiger; Ândrea Ribeiro-Dos-Santos
Journal:  Cancers (Basel)       Date:  2020-11-10       Impact factor: 6.639

7.  Alteration of Proteotranscriptomic Landscape Reveals the Transcriptional Regulatory Circuits Controlling Key-Signaling Pathways and Metabolic Reprogramming During Tumor Evolution.

Authors:  Geoffroy Andrieux; Sajib Chakraborty; Tonmoy Das; Melanie Boerries
Journal:  Front Cell Dev Biol       Date:  2020-12-15
  7 in total

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