Literature DB >> 18841879

Estrogen regulation of proteins in the rat ventromedial nucleus of the hypothalamus.

Bing Mo1, Eduardo Callegari, Martin Telefont, Kenneth J Renner.   

Abstract

The effects of estradiol (E2) on the expression of proteins in the pars lateralis of the ventromedial nucleus of the hypothalamus (VMNpl) in ovariectomized rats was studied using 2-dimensional gel electrophoresis followed by RPLC-nanoESI-MS/MS. E2 treatment resulted in the up-regulation of 29 identified proteins. Many of these proteins are implicated in the promotion of neuronal plasticity and signaling.

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Year:  2008        PMID: 18841879      PMCID: PMC2633946          DOI: 10.1021/pr8005974

Source DB:  PubMed          Journal:  J Proteome Res        ISSN: 1535-3893            Impact factor:   4.466


  75 in total

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