Literature DB >> 18840921

Development of Canadian screening tools for fetal alcohol spectrum disorder.

Y Ingrid Goh1, Albert E Chudley, Sterling K Clarren, Gideon Koren, Elaine Orrbine, Ted Rosales, Charlotte Rosenbaum.   

Abstract

BACKGROUND: Fetal alcohol spectrum disorder (FASD) is the most common cause of neurobehavioural handicap in North America. Screening for FASD may facilitate diagnosis and hence management of these children. We present a variety of screening tools for the identification of children at risk for FASD.
METHODS: We critically reviewed and evaluated published and practiced methods for their potential of screening suspected cases, their epidemiological characteristics (sensitivity, specificity, positive and negative predictive values) [Phase I], as well as their feasibility [Phase II].
RESULTS: The following five tools were selected for the FASD screening toolkit: screening fatty acid ethyl esters in neonatal meconium, the modified Child Behaviour Checklist, Medicine Wheel tool, Asante Centre Probation Officer Tool, and maternal history of drinking and drug use.
CONCLUSIONS: The toolkit for FASD screening aims at screening different populations, from the newborns to youth and at-risk mothers. It is anticipated that the toolkit will facilitate diagnosis of FASD.

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Year:  2008        PMID: 18840921

Source DB:  PubMed          Journal:  Can J Clin Pharmacol        ISSN: 1198-581X


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7.  Meconium fatty acid ethyl esters as biomarkers of late gestational ethanol exposure and indicator of ethanol-induced multi-organ injury in fetal sheep.

Authors:  Irene Zelner; Kelly Kenna; James F Brien; Alan Bocking; Richard Harding; David Walker; Gideon Koren
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10.  Fetal alcohol spectrum disorder: development of consensus referral criteria for specialist diagnostic assessment in Australia.

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Journal:  BMC Pediatr       Date:  2014-07-08       Impact factor: 2.125

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