Literature DB >> 18831154

Ira Remsen, saccharin, and the linear model.

Deborah J Warner1.   

Abstract

While working in the chemistry laboratory at Johns Hopkins University, Constantin Fahlberg oxidized the 'ortho-sulfamide of benzoic acid' and, by chance, found the result to be incredibly sweet. Several years later, now working on his own, he termed this stuff saccharin, developed methods of making it in quantity, obtained patents on these methods, and went into production. As the industrial and scientific value of saccharin became apparent, Ira Remsen pointed out that the initial work had been done in his laboratory and at his suggestion. The ensuing argument, carried out in the courts of law and public opinion, illustrates the importance of the linear model to scientists who staked their identities on the model of disinterested research but who also craved credit for important practical results.

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Year:  2008        PMID: 18831154     DOI: 10.1179/174582308X255415

Source DB:  PubMed          Journal:  Ambix        ISSN: 0002-6980            Impact factor:   0.750


  2 in total

1.  Ira Remsen, Osler, the Flexner Report, and the full-time plan.

Authors:  Charles S Bryan; Jonathan J Kopel; Mark Sorin
Journal:  Proc (Bayl Univ Med Cent)       Date:  2021-03-23

Review 2.  To a Question on the Mechanism of the Antimicrobial Action of Ortho-Benzoic Sulfimide.

Authors:  Ekaterina Y Kasap; Dmitry V Grishin
Journal:  Pharmaceuticals (Basel)       Date:  2020-12-13
  2 in total

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