Literature DB >> 18829469

Colon cancer: it's CIN or CIMP.

Jean-Pierre Issa1.   

Abstract

Combined genetic and epigenetic analysis of sporadic colon cancer suggest that it can no longer be viewed as a single disease. There are at least three different subsets with distinct clinico-pathologic features, with important implications for preventions, screening, and therapy.

Entities:  

Mesh：

Year:  2008        PMID： 18829469     DOI： 10.1158/1078-0432.CCR-08-1596

Source DB:  PubMed          Journal:  Clin Cancer Res        ISSN： 1078-0432            Impact factor:   12.531


  63 in total

1.  DNA methylation in the rectal mucosa is associated with crypt proliferation and fecal short-chain fatty acids.

Authors:  Daniel L Worthley; Vicki L J Whitehall; Richard K Le Leu; Natsumi Irahara; Ronald L Buttenshaw; Kylie-Ann Mallitt; Sonia A Greco; Ingunn Ramsnes; Jean Winter; Ying Hu; Shuji Ogino; Graeme P Young; Barbara A Leggett
Journal:  Dig Dis Sci       Date:  2010-07-16       Impact factor: 3.199

2.  Unique patterns of CpG island methylation in inflammatory bowel disease-associated colorectal cancers.

Authors:  Alexandru V Olaru; Yulan Cheng; Rachana Agarwal; Jian Yang; Stefan David; John M Abraham; Wayne Yu; John H Kwon; Mark Lazarev; Steven R Brant; Michael R Marohn; David F Hutcheon; Noam Harpaz; Stephen J Meltzer; Yuriko Mori
Journal:  Inflamm Bowel Dis       Date:  2011-08-09       Impact factor: 5.325

Review 3.  Functions of the APC tumor suppressor protein dependent and independent of canonical WNT signaling: implications for therapeutic targeting.

Authors:  William Hankey; Wendy L Frankel; Joanna Groden
Journal:  Cancer Metastasis Rev       Date:  2018-03       Impact factor: 9.264

4.  Increased EZH2 expression during the adenoma-carcinoma sequence in colorectal cancer.

Authors:  Mayuko Ohuchi; Yasuo Sakamoto; Ryuma Tokunaga; Yuki Kiyozumi; Kenichi Nakamura; Daisuke Izumi; Keisuke Kosumi; Kazuto Harada; Junji Kurashige; Masaaki Iwatsuki; Yoshifumi Baba; Yuji Miyamoto; Naoya Yoshida; Takashi Shono; Hideaki Naoe; Yutaka Sasaki; Hideo Baba
Journal:  Oncol Lett       Date:  2018-07-31       Impact factor: 2.967

5.  Post Genome-Wide Gene-Environment Interaction Study Using Random Survival Forest: Insulin Resistance, Lifestyle Factors, and Colorectal Cancer Risk.

Authors:  Su Yon Jung; Jeanette C Papp; Eric M Sobel; Zuo-Feng Zhang
Journal:  Cancer Prev Res (Phila)       Date:  2019-09-25

6.  Aneuploidy-associated gene expression signatures characterize malignant transformation in ulcerative colitis.

Authors:  Marco Gerling; Kari Nousiainen; Sampsa Hautaniemi; Stefan Krüger; Britta Fritzsche; Nils Homann; Hans-Peter Bruch; Gert Auer; Uwe J Roblick; Thomas Ried; Jens K Habermann
Journal:  Inflamm Bowel Dis       Date:  2013 Mar-Apr       Impact factor: 5.325

7.  HOXB13, a target of DNMT3B, is methylated at an upstream CpG island, and functions as a tumor suppressor in primary colorectal tumors.

Authors:  Kalpana Ghoshal; Tasneem Motiwala; Rainer Claus; Pearlly Yan; Huban Kutay; Jharna Datta; Sarmila Majumder; Shoumei Bai; Arnab Majumder; Tim Huang; Christoph Plass; Samson T Jacob
Journal:  PLoS One       Date:  2010-04-29       Impact factor: 3.752

Review 8.  Biomarkers of genome instability and cancer epigenetics.

Authors:  Adriana H O Reis; Fernando R Vargas; Bernardo Lemos
Journal:  Tumour Biol       Date:  2016-07-28

Review 9.  Somatic gene copy number alterations in colorectal cancer: new quest for cancer drivers and biomarkers.

Authors:  H Wang; L Liang; J-Y Fang; J Xu
Journal:  Oncogene       Date:  2015-08-10       Impact factor: 9.867

Review 10.  Emerging role of the β-catenin-PPARγ axis in the pathogenesis of colorectal cancer.

Authors:  Lina Sabatino; Massimo Pancione; Carolina Votino; Tommaso Colangelo; Angelo Lupo; Ettore Novellino; Antonio Lavecchia; Vittorio Colantuoni
Journal:  World J Gastroenterol       Date:  2014-06-21       Impact factor: 5.742
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.