Literature DB >> 18822166

Threshold for detection of diabetic peripheral sensory neuropathy using a range of research grade monofilaments in persons with Type 2 diabetes mellitus.

Mary P Thomson1, Julia Potter, Paul M Finch, Richard B Paisey.   

Abstract

AIMS: To identify the threshold of reduced sensory perception in Type 2 diabetes mellitus (Type 2 DM) using a range of research grade monofilaments.
METHODS: Three groups of participants were recruited into a between subject, cross-sectional study. Group 1(NEW), persons with Type 2 DM diagnosed for less than 2 years (n = 80); Group 2 (EST) persons with Type 2 DM diagnosed for more than 2 years (n = 91), and Group 3, a Comparison group without Type 2 DM (n = 73), resulted in a total study population, n = 244. Research grade monofilaments (2, 4, 6, 8 and 10-gram) were employed using standardised protocol, at 6 sites on the plantar aspect of both feet. The demographic and anthropometric measures of gender, age, height, weight, body mass index (BMI), blood pressure and duration of Type 2 DM since diagnosis (if applicable) of the participants were analysed.
RESULTS: Perception of the research grade monofilaments differed significantly between the 3 groups (p < 0.05). The 6-gram monofilament was found to be the threshold of normal perception, based on 90% of the Comparison group perceiving the 6-gram monofilament at all sites in contrast to 64% of NEW and 48% of EST groups.
CONCLUSION: The 6-gram monofilament was identified as the threshold of normal sensory perception. Inability to perceive the 6-gram monofilament indicates, when using the method described in this study, that diminution of sensory perception is evident. Employing a range of monofilaments, 6, 8 and 10-grams in Type 2 DM foot screening would allow the clinical detection of deteriorating sensory perception and enable implementation of foot protection strategies at an earlier stage than is currently practised.

Entities:  

Year:  2008        PMID: 18822166      PMCID: PMC2553781          DOI: 10.1186/1757-1146-1-9

Source DB:  PubMed          Journal:  J Foot Ankle Res        ISSN: 1757-1146            Impact factor:   2.303


  18 in total

1.  4-g monofilament is clinically useful for detecting diabetic peripheral neuropathy.

Authors:  Y Nagai; Y Sugiyama; T Abe; G Nomura
Journal:  Diabetes Care       Date:  2001-01       Impact factor: 19.112

2.  Screening techniques to identify people at high risk for diabetic foot ulceration: a prospective multicenter trial.

Authors:  H Pham; D G Armstrong; C Harvey; L B Harkless; J M Giurini; A Veves
Journal:  Diabetes Care       Date:  2000-05       Impact factor: 19.112

3.  Semmes-Weinstein monofilaments: a simple, effective and inexpensive screening device for identifying diabetic patients at risk of foot ulceration.

Authors:  S Kumar; D J Fernando; A Veves; E A Knowles; M J Young; A J Boulton
Journal:  Diabetes Res Clin Pract       Date:  1991-08       Impact factor: 5.602

4.  Sensory neuropathy in non-insulin-dependent diabetes mellitus. The San Luis Valley Diabetes Study.

Authors:  G M Franklin; L B Kahn; J Baxter; J A Marshall; R F Hamman
Journal:  Am J Epidemiol       Date:  1990-04       Impact factor: 4.897

Review 5.  Testing sensibility, including touch-pressure, two-point discrimination, point localization, and vibration.

Authors:  J Bell-Krotoski; S Weinstein; C Weinstein
Journal:  J Hand Ther       Date:  1993 Apr-Jun       Impact factor: 1.950

6.  Fifty years of somatosensory research: from the Semmes-Weinstein monofilaments to the Weinstein Enhanced Sensory Test.

Authors:  S Weinstein
Journal:  J Hand Ther       Date:  1993 Jan-Mar       Impact factor: 1.950

7.  A prospective study of risk factors for diabetic foot ulcer. The Seattle Diabetic Foot Study.

Authors:  E J Boyko; J H Ahroni; V Stensel; R C Forsberg; D R Davignon; D G Smith
Journal:  Diabetes Care       Date:  1999-07       Impact factor: 19.112

8.  Possible sources of discrepancies in the use of the Semmes-Weinstein monofilament. Impact on prevalence of insensate foot and workload requirements.

Authors:  M McGill; L Molyneaux; R Spencer; L F Heng; D K Yue
Journal:  Diabetes Care       Date:  1999-04       Impact factor: 19.112

9.  The prevalence of foot ulceration and its correlates in type 2 diabetic patients: a population-based study.

Authors:  S Kumar; H A Ashe; L N Parnell; D J Fernando; C Tsigos; R J Young; J D Ward; A J Boulton
Journal:  Diabet Med       Date:  1994-06       Impact factor: 4.359

10.  Role of neuropathy and high foot pressures in diabetic foot ulceration.

Authors:  R G Frykberg; L A Lavery; H Pham; C Harvey; L Harkless; A Veves
Journal:  Diabetes Care       Date:  1998-10       Impact factor: 19.112

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Authors:  Rachel E Ward; Robert M Boudreau; Paolo Caserotti; Tamara B Harris; Sasa Zivkovic; Bret H Goodpaster; Suzanne Satterfield; Stephen Kritchevsky; Ann V Schwartz; Aaron I Vinik; Jane A Cauley; Anne B Newman; Elsa S Strotmeyer
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2014-10-15       Impact factor: 6.053

5.  Prediction of incident diabetic neuropathy using the monofilament examination: a 4-year prospective study.

Authors:  Bruce A Perkins; Andrej Orszag; Mylan Ngo; Eduardo Ng; Patti New; Vera Bril
Journal:  Diabetes Care       Date:  2010-03-31       Impact factor: 19.112

6.  Trunk and foot acceleration variability during walking relates to fall history and clinical disability in persons with multiple sclerosis.

Authors:  Jordan J Craig; Adam P Bruetsch; Sharon G Lynch; Jessie M Huisinga
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7.  Prediction of protective sensory loss, neuropathy and foot ulceration in type 2 diabetes.

Authors:  R B Paisey; T Darby; A M George; M Waterson; P Hewson; C F Paisey; M P Thomson
Journal:  BMJ Open Diabetes Res Care       Date:  2016-05-05

8.  Treating peripheral neuropathy in individuals with type 2 diabetes mellitus with intraneural facilitation: a single blind randomized control trial.

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9.  Protection from clinical peripheral sensory neuropathy in Alström syndrome in contrast to early-onset type 2 diabetes.

Authors:  Richard B Paisey; Rosamund M Paisey; Mary P Thomson; Lynne Bower; Pietro Maffei; Julian P H Shield; Sue Barnett; Jan D Marshall
Journal:  Diabetes Care       Date:  2008-12-17       Impact factor: 19.112

10.  The effect of removing plugs and adding arch support to foam based insoles on plantar pressures in people with diabetic peripheral neuropathy.

Authors:  Tung-Liang Lin; Huey-Min Sheen; Chin-Teng Chung; Sai-Wei Yang; Shih-Yi Lin; Hong-Ji Luo; Chung-Yu Chen; I-Cheng Chan; Hsu-Sheng Shih; Wayne Huey-Herng Sheu
Journal:  J Foot Ankle Res       Date:  2013-07-29       Impact factor: 2.303

  10 in total

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