| Literature DB >> 18821562 |
Yulei Wang1, David N Keys, Janice K Au-Young, Caifu Chen.
Abstract
The unique properties of embryonic stem cells (ESCs) to self-renew indefinitely or to differentiate to any cell type have great potential for clinical applications in regenerative medicine. MicroRNAs (miRNAs) are emerging as important regulators of post-transcriptional gene expression and have been implicated as crucial elements in regulating ESCs. Here, we review recent progresses in characterizing the role of miRNAs in the maintenance and development of ESCs. (c) 2008 Wiley-Liss, Inc.Mesh:
Substances:
Year: 2009 PMID: 18821562 DOI: 10.1002/jcp.21607
Source DB: PubMed Journal: J Cell Physiol ISSN: 0021-9541 Impact factor: 6.384