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Literature DB >> 18821554

Inhibition of Mycobacterium tuberculosis pantothenate synthetase by analogues of the reaction intermediate.

Alessio Ciulli¹, Duncan E Scott, Michiyo Ando, Fernando Reyes, S Adrian Saldanha, Kellie L Tuck, Dimitri Y Chirgadze, Tom L Blundell, Chris Abell.

Abstract

Entities: Chemical

Mesh：

Substances：

Year: 2008 PMID： 18821554 PMCID： PMC4441726 DOI： 10.1002/cbic.200800437

Source DB: PubMed Journal: Chembiochem ISSN： 1439-4227 Impact factor: 3.164

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26 in total

Review 1. Novel targets for tuberculosis drug discovery.

Authors: Khisimuzi Mdluli; Melvin Spigelman
Journal: Curr Opin Pharmacol Date: 2006-08-09 Impact factor: 5.547

2. Rationally designed nucleoside antibiotics that inhibit siderophore biosynthesis of Mycobacterium tuberculosis.

Authors: Ravindranadh V Somu; Helena Boshoff; Chunhua Qiao; Eric M Bennett; Clifton E Barry; Courtney C Aldrich
Journal: J Med Chem Date: 2006-01-12 Impact factor: 7.446

3. Steady-state and pre-steady-state kinetic analysis of Mycobacterium tuberculosis pantothenate synthetase.

Authors: R Zheng; J S Blanchard
Journal: Biochemistry Date: 2001-10-30 Impact factor: 3.162

4. A novel inhibitor of Mycobacterium tuberculosis pantothenate synthetase.

Authors: E Lucile White; Kristen Southworth; Larry Ross; Sara Cooley; Rachel B Gill; Melinda Ingrum Sosa; Anna Manouvakhova; Lynn Rasmussen; Celia Goulding; David Eisenberg; Thomas M Fletcher
Journal: J Biomol Screen Date: 2006-12-14

5. The design and synthesis of inhibitors of pantothenate synthetase.

Authors: Kellie L Tuck; S Adrian Saldanha; Louise M Birch; Alison G Smith; Chris Abell
Journal: Org Biomol Chem Date: 2006-08-30 Impact factor: 3.876

Review 6. Biosynthesis of pantothenate.

Authors: Michael E Webb; Alison G Smith; Chris Abell
Journal: Nat Prod Rep Date: 2004-10-28 Impact factor: 13.423

7. Mycobacterium tuberculosis DeltaRD1 DeltapanCD: a safe and limited replicating mutant strain that protects immunocompetent and immunocompromised mice against experimental tuberculosis.

Authors: Vasan K Sambandamurthy; Steven C Derrick; Tsungda Hsu; Bing Chen; Michelle H Larsen; Kripa V Jalapathy; Mei Chen; John Kim; Steven A Porcelli; John Chan; Sheldon L Morris; William R Jacobs
Journal: Vaccine Date: 2006-06-12 Impact factor: 3.641

8. From genetic footprinting to antimicrobial drug targets: examples in cofactor biosynthetic pathways.

Authors: Svetlana Y Gerdes; Michael D Scholle; Mark D'Souza; Axel Bernal; Mark V Baev; Michael Farrell; Oleg V Kurnasov; Matthew D Daugherty; Faika Mseeh; Boris M Polanuyer; John W Campbell; Shubha Anantha; Konstantin Y Shatalin; Shamim A K Chowdhury; Michael Y Fonstein; Andrei L Osterman
Journal: J Bacteriol Date: 2002-08 Impact factor: 3.490

9. Active site residues in Mycobacterium tuberculosis pantothenate synthetase required in the formation and stabilization of the adenylate intermediate.

Authors: Renjian Zheng; Tarum K Dam; C Fred Brewer; John S Blanchard
Journal: Biochemistry Date: 2004-06-08 Impact factor: 3.162

10. A pantothenate auxotroph of Mycobacterium tuberculosis is highly attenuated and protects mice against tuberculosis.

Authors: Vasan K Sambandamurthy; Xiaojuan Wang; Bing Chen; Robert G Russell; Steven Derrick; Frank M Collins; Sheldon L Morris; William R Jacobs
Journal: Nat Med Date: 2002-09-09 Impact factor: 53.440

26 in total

Review 1. Adenylating enzymes in Mycobacterium tuberculosis as drug targets.

Authors: Benjamin P Duckworth; Kathryn M Nelson; Courtney C Aldrich
Journal: Curr Top Med Chem Date: 2012 Impact factor: 3.295

2. Integrated biophysical approach to fragment screening and validation for fragment-based lead discovery.

Authors: Hernani Leonardo Silvestre; Thomas L Blundell; Chris Abell; Alessio Ciulli
Journal: Proc Natl Acad Sci U S A Date: 2013-07-19 Impact factor: 11.205

3. Vitamins and cofactors: highlights of ESBOC 2009.

Authors: Edward McDonald
Journal: Nat Chem Biol Date: 2009-08 Impact factor: 15.040

4. Reaction intermediate analogues as bisubstrate inhibitors of pantothenate synthetase.

Authors: Zhixiang Xu; Wei Yin; Leonardo K Martinelli; Joanna Evans; Jinglei Chen; Yang Yu; Daniel J Wilson; Valerie Mizrahi; Chunhua Qiao; Courtney C Aldrich
Journal: Bioorg Med Chem Date: 2014-01-23 Impact factor: 3.641

5. Stable analogues of OSB-AMP: potent inhibitors of MenE, the o-succinylbenzoate-CoA synthetase from bacterial menaquinone biosynthesis.

Authors: Xuequan Lu; Rong Zhou; Indrajeet Sharma; Xiaokai Li; Gyanendra Kumar; Subramanyam Swaminathan; Peter J Tonge; Derek S Tan
Journal: Chembiochem Date: 2011-11-23 Impact factor: 3.164

6. Fragment screening of infectious disease targets in a structural genomics environment.

Authors: Darren W Begley; Douglas R Davies; Robert C Hartley; Thomas E Edwards; Bart L Staker; Wesley C Van Voorhis; Peter J Myler; Lance J Stewart
Journal: Methods Enzymol Date: 2011 Impact factor: 1.600

7. Improved Synthesis of Biotinol-5'-AMP: Implications for Antibacterial Discovery.

Authors: William Tieu; Steven W Polyak; Ashleigh S Paparella; Min Y Yap; Tatiana P Soares da Costa; Belinda Ng; Geqing Wang; Richard Lumb; Jan M Bell; John D Turnidge; Matthew C J Wilce; Grant W Booker; Andrew D Abell
Journal: ACS Med Chem Lett Date: 2014-12-11 Impact factor: 4.345