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Literature DB >> 18821121

Human herpesvirus 6 meningoradiculitis treated with intravenous immunoglobulin and valganciclovir.

Chafic Karam¹, Manuel Revuelta, Daniel Macgowan.

Abstract

Human herpesvirus 6 (HHV-6) is being increasingly associated with multiple neurological conditions. The authors report the case of a 26-year-old man with subacute meningoradiculitis initially treated with intravenous immunoglobulin. The cerebrospinal fluid (CSF) showed pleocytosis and polymerase chain reaction (PCR) was positive for HHV-6 type B DNA in the CSF and peripheral blood. He was subsequently treated with valganciclovir with near resolution of his symptoms.

Entities: Chemical Disease Species

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Year: 2008 PMID： 18821121 DOI： 10.1080/13550280802385513

Source DB: PubMed Journal: J Neurovirol ISSN： 1355-0284 Impact factor: 2.643

7 in total

1. Human herpesvirus 6 DNA levels in cerebrospinal fluid due to primary infection differ from those due to chromosomal viral integration and have implications for diagnosis of encephalitis.

Authors: Katherine N Ward; Hoe Nam Leong; Anton D Thiruchelvam; Claire E Atkinson; Duncan A Clark
Journal: J Clin Microbiol Date: 2007-01-17 Impact factor: 5.948

2. Herpesvirus DNA detection in cerebral spinal fluid: differences in clinical presentation between alpha-, beta-, and gamma-herpesviruses.

Authors: M Studahl; L Hagberg; E Rekabdar; T Bergström
Journal: Scand J Infect Dis Date: 2000

3. Human herpesvirus 6 chromosomal integration in immunocompetent patients results in high levels of viral DNA in blood, sera, and hair follicles.

Authors: Katherine N Ward; Hoe Nam Leong; Elisabeth P Nacheva; Julie Howard; Claire E Atkinson; Nicholas W S Davies; Paul D Griffiths; Duncan A Clark
Journal: J Clin Microbiol Date: 2006-04 Impact factor: 5.948

1 in total

Review 1. The leptomeninges as a critical organ for normal CNS development and function: First patient and public involved systematic review of arachnoiditis (chronic meningitis).

Authors: Carol S Palackdkharry; Stephanie Wottrich; Erin Dienes; Mohamad Bydon; Michael P Steinmetz; Vincent C Traynelis
Journal: PLoS One Date: 2022-09-30 Impact factor: 3.752

1 in total

Human herpesvirus 6 meningoradiculitis treated with intravenous immunoglobulin and valganciclovir.

1. Human herpesvirus 6 DNA levels in cerebrospinal fluid due to primary infection differ from those due to chromosomal viral integration and have implications for diagnosis of encephalitis.

2. Herpesvirus DNA detection in cerebral spinal fluid: differences in clinical presentation between alpha-, beta-, and gamma-herpesviruses.

3. Human herpesvirus 6 chromosomal integration in immunocompetent patients results in high levels of viral DNA in blood, sera, and hair follicles.

4. Atypical symptoms in patients with herpesvirus DNA detected by PCR in cerebrospinal fluid.

5. Human herpesvirus-6 infection in children. A prospective study of complications and reactivation.

6. Detection of human herpesvirus-6 in mesial temporal lobe epilepsy surgical brain resections.

7. Post-transplant acute limbic encephalitis: clinical features and relationship to HHV6.

Review 1. The leptomeninges as a critical organ for normal CNS development and function: First patient and public involved systematic review of arachnoiditis (chronic meningitis).