Literature DB >> 18819017

Relationship between susceptibility of Candida spp. isolates to amphotericin B and death or survival of patients with candidemia episodes.

Sydney Hartz Alves1, Everton Boff, Patricia Pozzatti, Liliane A Scheid, Erico de Loreto, Loiva T Ottoneli Oliveira, Valério Aquino, Luiz Carlos Severo, Janio Morais Santurio.   

Abstract

In this study, the susceptibility to amphotericin B of Candida spp. isolates obtained from patients with candidemia was related to their respective clinical outcomes. The susceptibility tests were carried out in three culture media: RPMI 1640, Antibiotic medium 3 and Yeast Nitrogen Base dextrose. We have found that minimal inhibitory concentrations and minimal fungicidal concentrations obtained using AM3 and YNBd media were significantly higher for Candida spp. from patients who died than for those from patients who survived the candidemia (P < 0.05). The assays with RPMI 1640 medium did not show these differences.

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Year:  2008        PMID: 18819017     DOI: 10.1007/s11046-008-9159-3

Source DB:  PubMed          Journal:  Mycopathologia        ISSN: 0301-486X            Impact factor:   2.574


  28 in total

1.  Correlation between in vitro susceptibility determined by E test and response to therapy with amphotericin B: results from a multicenter prospective study of candidemia.

Authors:  C J Clancy; M H Nguyen
Journal:  Antimicrob Agents Chemother       Date:  1999-05       Impact factor: 5.191

Review 2.  Antifungal susceptibility testing: practical aspects and current challenges.

Authors:  J H Rex; M A Pfaller; T J Walsh; V Chaturvedi; A Espinel-Ingroff; M A Ghannoum; L L Gosey; F C Odds; M G Rinaldi; D J Sheehan; D W Warnock
Journal:  Clin Microbiol Rev       Date:  2001-10       Impact factor: 26.132

3.  Reduced virulence of Candida albicans mutants affected in multidrug resistance.

Authors:  J M Becker; L K Henry; W Jiang; Y Koltin
Journal:  Infect Immun       Date:  1995-11       Impact factor: 3.441

4.  Do in vitro susceptibility data predict the microbiologic response to amphotericin B? Results of a prospective study of patients with Candida fungemia.

Authors:  M H Nguyen; C J Clancy; V L Yu; Y C Yu; A J Morris; D R Snydman; D A Sutton; M G Rinaldi
Journal:  J Infect Dis       Date:  1998-02       Impact factor: 5.226

5.  Evaluation of amphotericin B interpretive breakpoints for Candida bloodstream isolates by correlation with therapeutic outcome.

Authors:  Benjamin J Park; Beth A Arthington-Skaggs; Rana A Hajjeh; Naureen Iqbal; Meral A Ciblak; Wendy Lee-Yang; Mario D Hairston; Maureen Phelan; Brian D Plikaytis; Andre N Sofair; Lee H Harrison; Scott K Fridkin; David W Warnock
Journal:  Antimicrob Agents Chemother       Date:  2006-04       Impact factor: 5.191

6.  Amphotericin B resistance testing of Candida spp.: a comparison of methods.

Authors:  D Law; C B Moore; D W Denning
Journal:  J Antimicrob Chemother       Date:  1997-07       Impact factor: 5.790

7.  Development of amphotericin B-resistant Candida tropicalis in a patient with defective leukocyte function.

Authors:  D J Drutz; R I Lehrer
Journal:  Am J Med Sci       Date:  1978 Jul-Aug       Impact factor: 2.378

8.  Attributable mortality of nosocomial candidemia, revisited.

Authors:  Olafur Gudlaugsson; Shane Gillespie; Kathleen Lee; Jeff Vande Berg; Jianfang Hu; Shawn Messer; Loreen Herwaldt; Michael Pfaller; Daniel Diekema
Journal:  Clin Infect Dis       Date:  2003-10-08       Impact factor: 9.079

9.  Antifungal susceptibility survey of 2,000 bloodstream Candida isolates in the United States.

Authors:  Luis Ostrosky-Zeichner; John H Rex; Peter G Pappas; Richard J Hamill; Robert A Larsen; Harold W Horowitz; William G Powderly; Newton Hyslop; Carol A Kauffman; John Cleary; Julie E Mangino; Jeannette Lee
Journal:  Antimicrob Agents Chemother       Date:  2003-10       Impact factor: 5.191

10.  Incidence of polyene-resistant yeasts recovered from clinical specimens.

Authors:  J D Dick; W G Merz; R Saral
Journal:  Antimicrob Agents Chemother       Date:  1980-07       Impact factor: 5.191

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  1 in total

1.  In Vitro Susceptibility Testing in Fungi: What is its Role in Clinical Practice?

Authors:  Susanne Perkhofer; Cornelia Mrazek; Lukas Hartl; Cornelia Lass-Flörl
Journal:  Curr Infect Dis Rep       Date:  2010-11       Impact factor: 3.725

  1 in total

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