AIMS: To assess whether kidney transplantation improves sleep-related breathing disorders associated with hemodialysis. METHODS: A prospective study was carried out using full-night polysomnography. Nine hemodialysis patients (7 men and 2 women, aged 42 +/- 16.2 years, BMI 26 +/- 3.7) who later received a successful kidney transplantation were evaluated. Main sleep quality and respiratory variables were recorded: number of dips in oxygen saturation (SaO(2)) > or =3% per hour of sleep; percentage of sleep time with SaO(2) <90%; percentage of sleep time in apnea and hypopnea, and sleep apnea/hypopnea index (AHI). RESULTS: After kidney transplantation, the AHI improved in 8 of the 9 patients (10 +/- 10.7 vs. 4.9 +/- 6.1, p = 0.029). A decrease in the percentage of sleep time in apnea/hypopnea (5 +/- 6.8 vs. 0.7 +/- 1.1%, p = 0.008) and a reduction in the number of desaturations (25 +/- 26 vs. 12 +/- 11.2%, p = 0.010) were observed. CONCLUSIONS: Kidney transplantation improved respiratory events and nocturnal SaO(2) in hemodialysis patients. Copyright 2008 S. Karger AG, Basel.
AIMS: To assess whether kidney transplantation improves sleep-related breathing disorders associated with hemodialysis. METHODS: A prospective study was carried out using full-night polysomnography. Nine hemodialysis patients (7 men and 2 women, aged 42 +/- 16.2 years, BMI 26 +/- 3.7) who later received a successful kidney transplantation were evaluated. Main sleep quality and respiratory variables were recorded: number of dips in oxygen saturation (SaO(2)) > or =3% per hour of sleep; percentage of sleep time with SaO(2) <90%; percentage of sleep time in apnea and hypopnea, and sleep apnea/hypopnea index (AHI). RESULTS: After kidney transplantation, the AHI improved in 8 of the 9 patients (10 +/- 10.7 vs. 4.9 +/- 6.1, p = 0.029). A decrease in the percentage of sleep time in apnea/hypopnea (5 +/- 6.8 vs. 0.7 +/- 1.1%, p = 0.008) and a reduction in the number of desaturations (25 +/- 26 vs. 12 +/- 11.2%, p = 0.010) were observed. CONCLUSIONS: Kidney transplantation improved respiratory events and nocturnal SaO(2) in hemodialysis patients. Copyright 2008 S. Karger AG, Basel.
Authors: Katalin Z Ronai; Andras Szentkiralyi; Alpar S Lazar; Akos Ujszaszi; Csilla Turanyi; Ferenc Gombos; Istvan Mucsi; Robert Bodizs; Miklos Z Molnar; Marta Novak Journal: J Clin Sleep Med Date: 2017-04-15 Impact factor: 4.062
Authors: Srijan Tandukar; Surui Hou; Jonathan Yabes; Xinhui Ran; Mary Fletcher; Patrick Strollo; Sanjay R Patel; Mark Unruh; Manisha Jhamb Journal: Transplant Direct Date: 2019-05-29