Literature DB >> 18814167

Copper-catalyzed asymmetric conjugate addition of aryl aluminum reagents to trisubstituted enones: construction of aryl-substituted quaternary centers.

Christine Hawner1, Kangying Li, Virginie Cirriez, Alexandre Alexakis.   

Abstract

Entities:  

Year:  2008        PMID: 18814167     DOI: 10.1002/anie.200803436

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN: 1433-7851            Impact factor:   15.336


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  19 in total

1.  Mechanism and enantioselectivity in palladium-catalyzed conjugate addition of arylboronic acids to β-substituted cyclic enones: insights from computation and experiment.

Authors:  Jeffrey C Holder; Lufeng Zou; Alexander N Marziale; Peng Liu; Yu Lan; Michele Gatti; Kotaro Kikushima; K N Houk; Brian M Stoltz
Journal:  J Am Chem Soc       Date:  2013-09-27       Impact factor: 15.419

2.  Palladium-catalyzed asymmetric conjugate addition of arylboronic acids to five-, six-, and seven-membered β-substituted cyclic enones: enantioselective construction of all-carbon quaternary stereocenters.

Authors:  Kotaro Kikushima; Jeffrey C Holder; Michele Gatti; Brian M Stoltz
Journal:  J Am Chem Soc       Date:  2011-04-15       Impact factor: 15.419

3.  Enantioselective Construction of Acyclic Quaternary Carbon Stereocenters: Palladium-Catalyzed Decarboxylative Allylic Alkylation of Fully Substituted Amide Enolates.

Authors:  Pavel Starkov; Jared T Moore; Douglas C Duquette; Brian M Stoltz; Ilan Marek
Journal:  J Am Chem Soc       Date:  2017-07-07       Impact factor: 15.419

4.  Copper-catalyzed asymmetric conjugate addition of alkylzirconium reagents to cyclic enones to form quaternary centers.

Authors:  Philippe M C Roth; Mireia Sidera; Rebecca M Maksymowicz; Stephen P Fletcher
Journal:  Nat Protoc       Date:  2013-12-12       Impact factor: 13.491

5.  Synthesis of diverse β-quaternary ketones via palladium-catalyzed asymmetric conjugate addition of arylboronic acids to cyclic enones.

Authors:  Jeffrey C Holder; Emmett D Goodman; Kotaro Kikushima; Michele Gatti; Alexander N Marziale; Brian M Stoltz
Journal:  Tetrahedron       Date:  2014-11-28       Impact factor: 2.457

6.  Preparation of functionalized organoaluminiums by direct insertion of aluminium to unsaturated halides.

Authors:  Tobias Blümke; Yi-Hung Chen; Zhihua Peng; Paul Knochel
Journal:  Nat Chem       Date:  2010-03-24       Impact factor: 24.427

7.  Formation of vinyl-, vinylhalide- or acyl-substituted quaternary carbon stereogenic centers through NHC-Cu-catalyzed enantioselective conjugate additions of Si-containing vinylaluminums to β-substituted cyclic enones.

Authors:  Tricia L May; Jennifer A Dabrowski; Amir H Hoveyda
Journal:  J Am Chem Soc       Date:  2010-12-20       Impact factor: 15.419

8.  Quaternary carbon stereogenic centers through copper-catalyzed enantioselective allylic substitutions with readily accessible aryl- or heteroaryllithium reagents and aluminum chlorides.

Authors:  Fang Gao; Yunmi Lee; Kyoko Mandai; Amir H Hoveyda
Journal:  Angew Chem Int Ed Engl       Date:  2010-11-02       Impact factor: 15.336

9.  Preparation of (S)-tert-ButylPyOx and Palladium-catalyzed Asymmetric Conjugate Addition of Arylboronic Acids.

Authors:  Jeffrey C Holder; Samantha E Shockley; Mario P Wiesenfeldt; Hideki Shimizu; Brian M Stoltz
Journal:  Organic Synth       Date:  2016-03-04

10.  Palladium-Catalyzed Asymmetric Conjugate Addition of Arylboronic Acids to α,β-Unsaturated Cyclic Electrophiles.

Authors:  Samantha E Shockley; Jeffrey C Holder; Brian M Stoltz
Journal:  Org Process Res Dev       Date:  2015-07-02       Impact factor: 3.317

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