Literature DB >> 18813388

A soft-polymer piezoelectric bimorph cantilever-actuated peristaltic micropump.

Neil J Graf1, Michael T Bowser.   

Abstract

A peristaltic micropump was fabricated and characterized. The micropump was fabricated using soft lithography, and actuated using piezoelectric bimorph cantilevers. The micropump channel was formed by bonding two layers of PDMS, mixed at 5:1 and 30:1 ratios. The channel was fabricated in the 5:1 layer using replica molding (REM), where a very simple and inexpensive template was made by straddling a 75 microm wire over a glass substrate, followed by covering and smoothing over the wire with a piece of aluminium foil. Not only was this template inexpensive and extremely simple to fabricate, it also created a rounded cross-sectional geometry which is favorable for complete valve shutoff. The cantilevers were driven at Vp=+/-90 V with amplified square wave signals generated by a virtual function generator created in LabVIEW. Connections to the micropump were made by placing capillary tubes in the channel, and then sealed between the two layers of PDMS. Machined aluminium clamps were adhered to the tips of the cantilevers with general purpose adhesive. These clamps allowed for aluminium valves, with finely machined tips of dimensions 3 mm by 200 microm, to be held firmly in place. The variables characterized for this micropump were flow rate, maximum attainable backpressure, free cantilever deflection, valve shutoff, and valve leakage. Three actuation patterns with phase differences of 60, 90, and 120 degrees were compared for flow rate and maximum backpressure. It was determined that the 120 degrees signal outperformed the 60 degrees and 90 degrees signals for both maximum flowrate and maximum attainable backpressure. The maximum and minimum flowrates demonstrated by the micropump were 289 nL min(-1) and 53 nL min(-1), respectively. The maximum backpressure attained was 35 300 Pa. It was also demonstrated that the valves fully closed the channels upon actuation, with minimal observed leakage.

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Year:  2008        PMID: 18813388      PMCID: PMC2739037          DOI: 10.1039/b805252b

Source DB:  PubMed          Journal:  Lab Chip        ISSN: 1473-0189            Impact factor:   6.799


  12 in total

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Journal:  Anal Chem       Date:  2001-04-15       Impact factor: 6.986

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Authors:  Jun Xie; Jason Shih; Qiao Lin; Bozhi Yang; Yu-Chong Tai
Journal:  Lab Chip       Date:  2004-09-14       Impact factor: 6.799

6.  Hybrid sample-inverted reflow and soft-lithography technique for fabrication of conicoid microlens arrays.

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Journal:  Biomed Microdevices       Date:  2007-04       Impact factor: 2.838

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Authors:  D C Duffy; J C McDonald; O J Schueller; G M Whitesides
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Authors:  Debjani Paul; Antoine Pallandre; Sandrine Miserere; Jérémie Weber; Jean-Louis Viovy
Journal:  Electrophoresis       Date:  2007-04       Impact factor: 3.535

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Authors: 
Journal:  Science       Date:  1996-07-19       Impact factor: 47.728

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4.  Effect of cross sectional geometry on PDMS micro peristaltic pump performance: comparison of SU-8 replica molding vs. micro injection molding.

Authors:  Neil J Graf; Michael T Bowser
Journal:  Analyst       Date:  2013-10-07       Impact factor: 4.616

5.  Nucleic Acid-based Detection of Bacterial Pathogens Using Integrated Microfluidic Platform Systems.

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Journal:  Sensors (Basel)       Date:  2009-05-18       Impact factor: 3.576

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Authors:  Albert Chong; Zhonghua Sun; Lennart van de Velde; Shirley Jansen; Michel Versluis; Michel M P J Reijnen; Erik Groot Jebbink
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  7 in total

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