| Literature DB >> 1881331 |
S J Austin1, A Connelly, D G Gadian, J S Benton, E M Brett.
Abstract
Two children with Canavan's Disease, an autosomal recessive leukodystrophy, were studied by localized 1H spectroscopy. The N-acetylaspartate (NAA) signal intensity was high relative to other metabolite signals, and the signal intensity from choline-containing compounds was low. These findings are discussed in relation to a possible role for NAA in normal myelination.Entities:
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Year: 1991 PMID： 1881331 DOI： 10.1002/mrm.1910190235
Source DB: PubMed Journal: Magn Reson Med ISSN： 0740-3194 Impact factor: 4.668