| Literature DB >> 18813015 |
Abstract
Publications that compare randomized controlled trial and cohort study results on the effects of postmenopausal estrogen-plus-progestin therapy are reviewed. The 2 types of studies agree in identifying an early elevation in coronary heart disease risk, and a later developing elevation in breast cancer risk. Effects among women who begin hormone therapy within a few years after the menopause may be comparatively more favorable for coronary heart disease and less favorable for breast cancer. These analyses illustrate the potential of modern data analysis methods to enhance the reliability and interpretation of epidemiologic data.Entities:
Mesh:
Substances:
Year: 2008 PMID: 18813015 PMCID: PMC2711000 DOI: 10.1097/EDE.0b013e318188e83b
Source DB: PubMed Journal: Epidemiology ISSN: 1044-3983 Impact factor: 4.822