Literature DB >> 18811570

Safety and outcome of percutaneous nephrolithotomy in the elderly: retrospective comparison to a younger patient group.

Theodore Anagnostou1, Trevor Thompson, Chi-Fai Ng, Sami Moussa, Gordon Smith, David A Tolley.   

Abstract

AIM: To evaluate whether the overall safety and efficacy profile of percutaneous surgery for urinary stone disease in older (>70 years) patients might influence the decision for the procedure in the elderly.
MATERIALS AND METHODS: A large database was created from our patients (n = 1058) who underwent percutaneous surgery for stone disease between 1991 and 2003 in the Scottish Lithotriptor Centre, including clinical and operation details for each case. Only percutaneous nephrolithotomy cases with full details were studied (n = 779) and were grouped into two age groups: (1) between 17 and 69 years and (2) over 70 years. Statistical analysis evaluated differences in terms of operation-related adverse events, stone-free success rates, and clinical success rates (including stone-free cases and cases with residual fragments <4 mm). Further analysis was performed for the same endpoints after stratification of the patients by (1) previous stone procedures and (2) special clinical features.
RESULTS: In the overall database, no statistically important differences were found between the two groups in terms of stone burden before surgery, adverse events rates, complete stone-free rates, and clinical success rates. However, a statistical trend toward higher clinical success rates in favor of the younger group was seen (P = 0.051). Stratification of our database according to previous stone disease procedures or special clinical or anatomic characteristics has only shown a statistically important difference for clinical success rates in favor of the older group without special features (P = 0.01).
CONCLUSION: In experienced hands, age-related morbidity or age itself should not be a discouraging consideration when deciding on performing percutaneous nephrolithotomy, as the procedure is as equally feasible and safe in the elderly as in the younger patient population.

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Year:  2008        PMID: 18811570     DOI: 10.1089/end.2007.0432

Source DB:  PubMed          Journal:  J Endourol        ISSN: 0892-7790            Impact factor:   2.942


  4 in total

1.  Does aging affect the outcome of percutaneous nephrolithotomy?

Authors:  Ibrahım Buldu; Abdulkadir Tepeler; Tuna Karatag; Mehmet Nuri Bodakci; Namık Kemal Hatipoglu; Necmettin Penbegul; Tolga Akman; Okan Istanbulluoglu; Abdullah Armagan
Journal:  Urolithiasis       Date:  2014-11-14       Impact factor: 3.436

2.  Percutaneous nephrolithotomy for staghorn kidney stones in elderly patients.

Authors:  Baris Kuzgunbay; Tahsin Turunc; Ozgur Yaycioglu; Aliye Atay Kayis; Umit Gul; Tulga Egilmez; Cem Aygun; Hakan Ozkardes
Journal:  Int Urol Nephrol       Date:  2010-12-29       Impact factor: 2.370

3.  Lessons learned from the CROES percutaneous nephrolithotomy global study.

Authors:  Guido M Kamphuis; Joyce Baard; Matias Westendarp; Jean J M C H de la Rosette
Journal:  World J Urol       Date:  2014-08-07       Impact factor: 4.226

4.  Metabolic assessment of elderly men with urolithiasis.

Authors:  Celso Heitor Freitas Junior; Eduardo Mazzucchi; Alexandre Danilovic; Artur Henrique Brito; Miguel Srougi
Journal:  Clinics (Sao Paulo)       Date:  2012       Impact factor: 2.365

  4 in total

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