Literature DB >> 18809431

Chitosan/polyethylene glycol diacrylate films as potential wound dressing material.

Xiaodan Zhang1, Dongzhi Yang, Jun Nie.   

Abstract

Michael addition reaction of Chitosan (CS) and polyethylene glycol diacrylate (PEGDA) was carried out successfully in acidic solution. Films with CS/PEGDA weight ratios from 100/0 to 0/100 in 10% increments were analyzed by Fourier transform infrared (FTIR) spectroscopy, Scanning Electron Microscope (SEM) and X-Ray Diffraction (XRD). Additionally, the films were characterized by measuring mechanical property, swelling property. The potential application of the CS/PEGDA film as wound dressing material was evaluated in vitro by using mouse fibroblasts (L929) as reference cell lines, indirect cytotoxicity assessment indicated that CS/PEGDA films were nontoxic to L929 cell.

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Year:  2008        PMID： 18809431     DOI： 10.1016/j.ijbiomac.2008.08.010

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN： 0141-8130            Impact factor:   6.953


  11 in total

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