Literature DB >> 18809063

Do additional shaved margins at the time of lumpectomy eliminate the need for re-excision?

Allyson F Jacobson1, Juhi Asad, Susan K Boolbol, Michael P Osborne, Kwadwo Boachie-Adjei, Sheldon M Feldman.   

Abstract

BACKGROUND: Most women diagnosed with breast cancer undergo breast-conservation surgery. Re-excision rates for positive margins have been reported to be greater than 50%. The purpose of our study was to determine if removing additional shaved margins from the lumpectomy cavity at the time of lumpectomy reduces re-excisions.
METHODS: A retrospective study was performed on 125 women who had undergone lumpectomy with additional shaved margins taken from the lumpectomy cavity. Pathology reports were reviewed for tumor size and histology, lumpectomy and additional margin status, and specimen and margin volume.
RESULTS: If additional margins were not taken, 66% would have required re-excision. Because of taking additional shaved margins, re-excision was eliminated in 48%.
CONCLUSION: Excising additional shaved margins at the original surgery reduced reoperations by 48%. There is a balance between removing additional margins and desirable cosmesis after breast-conservation surgery. The decision to take extra margins should be based on the surgeon's judgment.

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Year:  2008        PMID: 18809063     DOI: 10.1016/j.amjsurg.2008.06.007

Source DB:  PubMed          Journal:  Am J Surg        ISSN: 0002-9610            Impact factor:   2.565


  21 in total

Review 1.  Appropriate margin for lumpectomy excision of invasive breast cancer.

Authors:  Andrea V Barrio; Monica Morrow
Journal:  Chin Clin Oncol       Date:  2016-04-07

2.  Efficacy of intraoperative entire-circumferential frozen section analysis of lumpectomy margins during breast-conserving surgery for breast cancer.

Authors:  Tomofumi Osako; Reiki Nishimura; Yasuyuki Nishiyama; Yasuhiro Okumura; Rumiko Tashima; Masahiro Nakano; Mamiko Fujisue; Yasuo Toyozumi; Nobuyuki Arima
Journal:  Int J Clin Oncol       Date:  2015-04-09       Impact factor: 3.402

3.  The effect of simultaneous peripheral excision in breast conservation upon margin status.

Authors:  Roshani R Patel; Tianyu Li; Eric A Ross; Linda Sesa; Elin R Sigurdson; Richard J Bleicher
Journal:  Ann Surg Oncol       Date:  2010-06-12       Impact factor: 5.344

4.  A Randomized, Controlled Trial of Cavity Shave Margins in Breast Cancer.

Authors:  Anees B Chagpar; Brigid K Killelea; Theodore N Tsangaris; Meghan Butler; Karen Stavris; Fangyong Li; Xiaopan Yao; Veerle Bossuyt; Malini Harigopal; Donald R Lannin; Lajos Pusztai; Nina R Horowitz
Journal:  N Engl J Med       Date:  2015-05-30       Impact factor: 91.245

5.  Does cavity margin shaving reduce residual tumor and re-excision rates? A systematic review.

Authors:  M Fernandez-Pacheco; O Ortmann; A Ignatov; E C Inwald
Journal:  Arch Gynecol Obstet       Date:  2022-05-20       Impact factor: 2.344

6.  Impact of margin assessment method on positive margin rate and total volume excised.

Authors:  Tracy-Ann Moo; Lydia Choi; Candice Culpepper; Cristina Olcese; Alexandra Heerdt; Lisa Sclafani; Tari A King; Anne S Reiner; Sujata Patil; Edi Brogi; Monica Morrow; Kimberly J Van Zee
Journal:  Ann Surg Oncol       Date:  2013-09-18       Impact factor: 5.344

7.  Economic Impact of Routine Cavity Margins Versus Standard Partial Mastectomy in Breast Cancer Patients: Results of a Randomized Controlled Trial.

Authors:  Anees B Chagpar; Nina R Horowitz; Brigid K Killelea; Theodore Tsangaris; Peter Longley; Sonia Grizzle; Michael Loftus; Fangyong Li; Meghan Butler; Karen Stavris; Xiaopan Yao; Malini Harigopal; Veerle Bossuyt; Donald R Lannin; Lajos Pusztai; Amy J Davidoff; Cary P Gross
Journal:  Ann Surg       Date:  2017-01       Impact factor: 12.969

8.  Rapid noninvasive optical imaging of tissue composition in breast tumor margins.

Authors:  Lee G Wilke; J Quincy Brown; Torre M Bydlon; Stephanie A Kennedy; Lisa M Richards; Marlee K Junker; Jennifer Gallagher; William T Barry; Joseph Geradts; Nimmi Ramanujam
Journal:  Am J Surg       Date:  2009-10       Impact factor: 2.565

9.  Higher Volume at Time of Breast Conserving Surgery Reduces Re-Excision in DCIS.

Authors:  J H Wolf; Y Wen; D Axelrod; D Roses; A Guth; R Shapiro; J Cohen; B Singh
Journal:  Int J Surg Oncol       Date:  2011-03-09

10.  Re-Excision Rates in Breast-Conserving Surgery for Invasive Breast Cancer after Neoadjuvant Chemotherapy with and without the Use of a Radiopaque Tissue Transfer and X-ray System.

Authors:  Suniza Jamaris; Leyla Akpolat-Basci; Miltiades Stephanou; Sarah Wetzig; Yueksel Cubuk; Johannes Gerharz; Ann-Kathrin Bittner; Mee Hoong See; Cornelia Liedtke; Hans-Christian Kolberg
Journal:  Breast Care (Basel)       Date:  2018-11-14       Impact factor: 2.860

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