Literature DB >> 18804170

A survey of nonribosomal peptide synthetase (NRPS) genes in Aspergillus nidulans.

Hans von Döhren1.   

Abstract

The genome of Aspergillus nidulans carries 27 genes encoding nonribosomal peptide synthetase (NRPS) structures, although only five of these forming peptides and amino acid containing metabolites have been identified so far. This manuscript describes domain structures, substrate binding pockets and related genes and gene clusters and summarizes our current state of product prediction of fungal NRPS systems.

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Year:  2008        PMID: 18804170     DOI: 10.1016/j.fgb.2008.08.008

Source DB:  PubMed          Journal:  Fungal Genet Biol        ISSN: 1087-1845            Impact factor:   3.495


  36 in total

1.  Activation of a silent fungal polyketide biosynthesis pathway through regulatory cross talk with a cryptic nonribosomal peptide synthetase gene cluster.

Authors:  Sebastian Bergmann; Alexander N Funk; Kirstin Scherlach; Volker Schroeckh; Ekaterina Shelest; Uwe Horn; Christian Hertweck; Axel A Brakhage
Journal:  Appl Environ Microbiol       Date:  2010-10-15       Impact factor: 4.792

Review 2.  Microbial natural products: molecular blueprints for antitumor drugs.

Authors:  Lesley-Ann Giddings; David J Newman
Journal:  J Ind Microbiol Biotechnol       Date:  2013-09-03       Impact factor: 3.346

Review 3.  Regulation of fungal secondary metabolism.

Authors:  Axel A Brakhage
Journal:  Nat Rev Microbiol       Date:  2012-11-26       Impact factor: 60.633

4.  Molecular genetic analysis reveals that a nonribosomal peptide synthetase-like (NRPS-like) gene in Aspergillus nidulans is responsible for microperfuranone biosynthesis.

Authors:  Hsu-Hua Yeh; Yi-Ming Chiang; Ruth Entwistle; Manmeet Ahuja; Kuan-Han Lee; Kenneth S Bruno; Tung-Kung Wu; Berl R Oakley; Clay C C Wang
Journal:  Appl Microbiol Biotechnol       Date:  2012-05-25       Impact factor: 4.813

5.  Alternative splicing acting as a bridge in evolution.

Authors:  Kemin Zhou; Asaf Salamov; Alan Kuo; Andrea L Aerts; Xiangyang Kong; Igor V Grigoriev
Journal:  Stem Cell Investig       Date:  2015-10-30

6.  Biosynthetic Cyclization Catalysts for the Assembly of Peptide and Polyketide Natural Products.

Authors:  Maria L Adrover-Castellano; Jennifer J Schmidt; David H Sherman
Journal:  ChemCatChem       Date:  2021-01-28       Impact factor: 5.686

7.  Aspergillus mulundensis sp. nov., a new species for the fungus producing the antifungal echinocandin lipopeptides, mulundocandins.

Authors:  Gerald F Bills; Qun Yue; Li Chen; Yan Li; Zhiqiang An; Jens C Frisvad
Journal:  J Antibiot (Tokyo)       Date:  2015-10-14       Impact factor: 2.649

8.  Phylogenetic analysis of fungal ABC transporters.

Authors:  Andriy Kovalchuk; Arnold J M Driessen
Journal:  BMC Genomics       Date:  2010-03-16       Impact factor: 3.969

9.  Structure of a eukaryotic nonribosomal peptide synthetase adenylation domain that activates a large hydroxamate amino acid in siderophore biosynthesis.

Authors:  T Verne Lee; Linda J Johnson; Richard D Johnson; Albert Koulman; Geoffrey A Lane; J Shaun Lott; Vickery L Arcus
Journal:  J Biol Chem       Date:  2009-11-18       Impact factor: 5.157

10.  Breaking the silence: protein stabilization uncovers silenced biosynthetic gene clusters in the fungus Aspergillus nidulans.

Authors:  Jennifer Gerke; Ozgür Bayram; Kirstin Feussner; Manuel Landesfeind; Ekaterina Shelest; Ivo Feussner; Gerhard H Braus
Journal:  Appl Environ Microbiol       Date:  2012-09-21       Impact factor: 4.792

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