Literature DB >> 18803431

Assessing the value-adding impact of diagnostic-type tests on drug development and marketing.

Edward D Blair1.   

Abstract

OBJECTIVE AND METHODS: We explore the cash value of the companion diagnostics opportunity from the perspective of the pharmaceutical partner. Cashflow-based modeling is used to demonstrate the potential financial benefits of key relationships between the pharmaceutical and diagnostics industries.
RESULTS: In four scenarios, the uplift in the net present value (NPV) of a proprietary medicine can exceed $US1.8 billion. By simple extrapolation, the uplifted NPV calculations allow realistic and plausible estimates of the companion diagnostic opportunity to be in the region of $US40 billion to $US90 billion.
CONCLUSION: It is expected that such market valuation could drive a macroeconomic change that shifts healthcare practice from reactionary disease-treatment to proactive health maintenance.

Mesh:

Year:  2008        PMID: 18803431     DOI: 10.1007/BF03256298

Source DB:  PubMed          Journal:  Mol Diagn Ther        ISSN: 1177-1062            Impact factor:   4.074


  6 in total

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4.  Integrating molecular medicine into the US health-care system: opportunities, barriers, and policy challenges.

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5.  Is personalized medicine finally arriving?

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Review 6.  Stratified medicine: strategic and economic implications of combining drugs and clinical biomarkers.

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  6 in total
  2 in total

Review 1.  Aligning the economic value of companion diagnostics and stratified medicines.

Authors:  Edward D Blair; Elyse K Stratton; Martina Kaufmann
Journal:  J Pers Med       Date:  2012-11-26

2.  Scientific challenges and implementation barriers to translation of pharmacogenomics in clinical practice.

Authors:  Y W Francis Lam
Journal:  ISRN Pharmacol       Date:  2013-02-28
  2 in total

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