Literature DB >> 18789505

Local autogenous bone mixed with bone expander: an optimal option of bone graft in single-segment posterolateral lumbar fusion.

Chia-Hao Chang1, Mou-Zen Lin, Yen-Jen Chen, Horng-Chaung Hsu, Hsien-Te Chen.   

Abstract

BACKGROUND: This was a retrospective study of clinical results for single-segment posterolateral lumbar fusion using local autograft bone with bone expander.
METHODS: Sixty-six patients underwent single-segment decompression with instrumented posterolateral fusion. Locally harvested morselized bone from the decompressive site mixed with 2 mL calcium sulfate (OSTEOSET, Wright Medical Technology, Arlington, TN, USA) was used for the fusion at the posterolateral aspect of the lumbar spine. The minimum follow-up period was 15 months. The status of the fusion was evaluated by plain film, flexion-extension view, and fine-cut computed tomography (CT) with coronal reconstruction. Radiographic fusion criteria included less than 5 degrees of angular motion, less than 2 mm of translation, and evidence of bridging bone in the posterolateral lumbar area on the CT scan. The clinical outcome was recorded using VAS score and the ODI. The results were then compared with the result of the other group who had received the same procedure except that a pure autogenous bone graft harvested from the PSIS was used.
RESULTS: In the group using local bone and OSTEOSET, the fusion rate was 92.3% by the strict criteria. The VAS scores for leg pain and back pain were decreased in the 2 groups, but there was no significant difference between them. The improvement in the ODI was also similar between the 2 groups. Intraoperative blood loss and the time needed for the operation were significantly decreased in the group using local bone and OSTEOSET as the bone graft. In the group using autogenous bone graft, donor site morbidity was still encountered.
CONCLUSIONS: Using local laminectomy bone with calcium sulfate as bone graft is a practical option in posterolateral lumbar fusion with the advantages of less operative time, less blood loss, and avoidance of donor site morbidity.

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Year:  2008        PMID: 18789505     DOI: 10.1016/j.surneu.2008.05.022

Source DB:  PubMed          Journal:  Surg Neurol        ISSN: 0090-3019


  7 in total

1.  Bone substitutes and expanders in Spine Surgery: A review of their fusion efficacies.

Authors:  Abhijeet Kadam; Paul W Millhouse; Christopher K Kepler; Kris E Radcliff; Michael G Fehlings; Michael E Janssen; Rick C Sasso; James J Benedict; Alexander R Vaccaro
Journal:  Int J Spine Surg       Date:  2016-09-22

Review 2.  A systematic review of comparative studies on bone graft alternatives for common spine fusion procedures.

Authors:  Charla R Fischer; Ryan Cassilly; Winifred Cantor; Emmanuel Edusei; Qusai Hammouri; Thomas Errico
Journal:  Eur Spine J       Date:  2013-02-26       Impact factor: 3.134

3.  Radiographic Analysis of Instrumented Posterolateral Fusion Mass Using Mixture of Local Autologous Bone and b-TCP (PolyBone®) in a Lumbar Spinal Fusion Surgery.

Authors:  Jin Hoon Park; Chung Gon Choi; Sang Ryong Jeon; Seung Chul Rhim; Chang Jin Kim; Sung Woo Roh
Journal:  J Korean Neurosurg Soc       Date:  2011-05-31

Review 4.  Improving the clinical evidence of bone graft substitute technology in lumbar spine surgery.

Authors:  Wellington K Hsu; M S Nickoli; J C Wang; J R Lieberman; H S An; S T Yoon; J A Youssef; D S Brodke; C M McCullough
Journal:  Global Spine J       Date:  2012-10-09

5.  Bone grafting options for lumbar spine surgery: a review examining clinical efficacy and complications.

Authors:  Kenneth Vaz; Kushagra Verma; Themistocles Protopsaltis; Frank Schwab; Baron Lonner; Thomas Errico
Journal:  SAS J       Date:  2010-09-01

6.  Clinical evaluation of an allogeneic bone matrix containing viable osteogenic cells in patients undergoing one- and two-level posterolateral lumbar arthrodesis with decompressive laminectomy.

Authors:  David B Musante; Michael E Firtha; Brent L Atkinson; Rebekah Hahn; James T Ryaby; Raymond J Linovitz
Journal:  J Orthop Surg Res       Date:  2016-05-27       Impact factor: 2.359

Review 7.  Ceramic-based bone grafts as a bone grafts extender for lumbar spine arthrodesis: a systematic review.

Authors:  Michael S Nickoli; Wellington K Hsu
Journal:  Global Spine J       Date:  2014-06-09
  7 in total

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