BACKGROUND: Gastroesophageal reflux (GER) is common in children with congenital diaphragmatic hernia (CDH), and the optimal management in these patients is not well established. The aim of this study was to assess whether a preventive fundoplication performed during the first surgery will improve GER and nutritional morbidity in patients with a left CDH. METHODS: Thus we studied one group of 17 patients treated with a one-step antireflux procedure (group A) and a group of 19 patients with only initial diaphragmatic repair (group B) between January 1994 and December 2004. The patients were classified in three stages, mild intermediate and severe form, based on anatomic criteria (liver position and patch requirement). Most of the patients with the severe form of disease were in group A. Clinical charts were compared between the two groups with a mean follow-up of 3 years. RESULTS: For patients with intra-abdominal liver and direct diaphragmatic closure, the duration of hospitalization was significantly longer in group A than in group B (p = 0.08). The incidence of GER was significantly lower in group A (17.6%) than in group B (52.6%) at 1-year follow-up (p < 0.5). In the last group, 30% required a fundoplication before 6 months. Seven patients (19%) required intermittent nutritional supplementation via nasogastric tube feeding; for these patients there was no difference between the two groups. A gastrostomy was performed in only one patient. Twelve percent of patients had growth retardation during most of their first year, again with no difference between the two groups. CONCLUSIONS: Based on the published data, recommendations can be made regarding the efficacy of adding an antireflux surgery procedure to left CDH repair in only patients with intrathoracic liver and/or patch requirement.
BACKGROUND: Gastroesophageal reflux (GER) is common in children with congenital diaphragmatic hernia (CDH), and the optimal management in these patients is not well established. The aim of this study was to assess whether a preventive fundoplication performed during the first surgery will improve GER and nutritional morbidity in patients with a left CDH. METHODS: Thus we studied one group of 17 patients treated with a one-step antireflux procedure (group A) and a group of 19 patients with only initial diaphragmatic repair (group B) between January 1994 and December 2004. The patients were classified in three stages, mild intermediate and severe form, based on anatomic criteria (liver position and patch requirement). Most of the patients with the severe form of disease were in group A. Clinical charts were compared between the two groups with a mean follow-up of 3 years. RESULTS: For patients with intra-abdominal liver and direct diaphragmatic closure, the duration of hospitalization was significantly longer in group A than in group B (p = 0.08). The incidence of GER was significantly lower in group A (17.6%) than in group B (52.6%) at 1-year follow-up (p < 0.5). In the last group, 30% required a fundoplication before 6 months. Seven patients (19%) required intermittent nutritional supplementation via nasogastric tube feeding; for these patients there was no difference between the two groups. A gastrostomy was performed in only one patient. Twelve percent of patients had growth retardation during most of their first year, again with no difference between the two groups. CONCLUSIONS: Based on the published data, recommendations can be made regarding the efficacy of adding an antireflux surgery procedure to left CDH repair in only patients with intrathoracic liver and/or patch requirement.
Authors: Priscilla P L Chiu; Carolien Sauer; Alexandra Mihailovic; Ian Adatia; Desmond Bohn; Allan L Coates; Jacob C Langer Journal: J Pediatr Surg Date: 2006-05 Impact factor: 2.545
Authors: Anna Maria Caruso; Maria Rita Di Pace; Pieralba Catalano; Fabiana Farina; Alessandra Casuccio; Marcello Cimador; Enrico De Grazia Journal: Pediatr Surg Int Date: 2013-04-10 Impact factor: 1.827
Authors: Christoph von Schrottenberg; Susanne Deeg; Christel Weiss; Rüdiger Adam; Lucas M Wessel; Michael Boettcher; Katrin B Zahn Journal: Children (Basel) Date: 2022-07-29
Authors: Laura C Guglielmetti; Arturo E Estrada; Ryan Phillips; Ralph F Staerkle; Jason Gien; John P Kinsella; Kenneth W Liechty; Ahmed I Marwan; Raphael N Vuille-Dit-Bille Journal: Medicine (Baltimore) Date: 2020-12-04 Impact factor: 1.817