Literature DB >> 1878423

Effects of suramin on phagocytes in vitro.

S Sipka1, K Dankó, P Nagy, V Taskov, L Dénes, L Czirják, G Szegedi.   

Abstract

In the therapeutically important range (100-200 micrograms/ml), suramin was found to increase the phagocytic activity of human monocytes (measured by the uptake of Saccharomyces cerevisiae and sensitized sheep red blood cells) in vitro. Suramin itself was a chemotactic signal for monocytes and increased the chemiluminescence of neutrophil granulocytes. Suramin seems to act via the ATP-binding P2 receptors of human phagocytes.

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Year:  1991        PMID： 1878423     DOI： 10.1007/bf01714961

Source DB:  PubMed          Journal:  Ann Hematol        ISSN： 0939-5555            Impact factor:   3.673


  17 in total

1.  Studies on suramin; the action of the drug on enzymes and some other proteins. General considerations.

Authors:  B W TOWN; E D WILLS; E J WILSON; A WORMALL
Journal:  Biochem J       Date:  1950-08       Impact factor: 3.857

Review 2.  Extracellular ATP: effects, sources and fate.

Authors:  J L Gordon
Journal:  Biochem J       Date:  1986-01-15       Impact factor: 3.857

3.  Suramin: a potent inhibitor of the reverse transcriptase of RNA tumor viruses.

Authors:  E De Clercq
Journal:  Cancer Lett       Date:  1979-11       Impact factor: 8.679

4.  Effects of suramin on HTLV-III/LAV infection presenting as Kaposi's sarcoma or AIDS-related complex: clinical pharmacology and suppression of virus replication in vivo.

Authors:  S Broder; R Yarchoan; J M Collins; H C Lane; P D Markham; R W Klecker; R R Redfield; H Mitsuya; D F Hoth; E Gelmann
Journal:  Lancet       Date:  1985-09-21       Impact factor: 79.321

5.  Suramin antagonizes responses to P2-purinoceptor agonists and purinergic nerve stimulation in the guinea-pig urinary bladder and taenia coli.

Authors:  C H Hoyle; G E Knight; G Burnstock
Journal:  Br J Pharmacol       Date:  1990-03       Impact factor: 8.739

6.  [Chemiluminescence measurement in AIDS, lymphadenopathy and hemophilia patients].

Authors:  L Stöhr; P Altmeyer; M J Sessler; I Scharrer; E B Helm; H Holzmann
Journal:  Z Hautkr       Date:  1985-08-01

7.  Effects of immune complexes from SLE patients on human monocyte locomotion and Fc receptor function.

Authors:  K Lukács; M Kávai; A Bányai; I Sonkoly; E Végh; G Szabó; G Szegedi
Journal:  Ann Rheum Dis       Date:  1984-10       Impact factor: 19.103

8.  Hydrogen peroxide metabolism in human monocytes during differentiation in vitro.

Authors:  A Nakagawara; C F Nathan; Z A Cohn
Journal:  J Clin Invest       Date:  1981-11       Impact factor: 14.808

9.  Functional evidence for involvement of P2 purinoceptors in the ATP stimulation of phosphatidylcholine secretion in type II alveolar epithelial cells.

Authors:  A M Gilfillan; S A Rooney
Journal:  Biochim Biophys Acta       Date:  1988-03-04

10.  Generation of superoxide anion and chemiluminescence by human monocytes during phagocytosis and on contact with surface-bound immunoglobulin G.

Authors:  R B Johnston; J E Lehmeyer; L A Guthrie
Journal:  J Exp Med       Date:  1976-06-01       Impact factor: 14.307
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  1 in total

1.  The effect of suramin on healing adult rodent dermal wounds.

Authors:  J Chamberlain; M Shah; M W Ferguson
Journal:  J Anat       Date:  1995-02       Impact factor: 2.610
  1 in total

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