Literature DB >> 178824

Generation of superoxide anion and chemiluminescence by human monocytes during phagocytosis and on contact with surface-bound immunoglobulin G.

R B Johnston, J E Lehmeyer, L A Guthrie.   

Abstract

Extent of O-2-release and chemiluminescence, attributed to singlet oxygen, has been compared in human monocytes and neutrophils during phagocytosis, stimulation by the surface-active agent phorbol myristate acetate, or contact with aggregated IgG in a model of immune complex disease. Monocytes generated O-2-and chemiluminescence with each of the three stimuli, although values were significantly less than those of neutrophils from the same individuals. Lymphocytes had no significant activity in either assay with any stimulus. Oxygen metabolites released from mononuclear phagocytes are highly reactive and could play a part in both the beneficial and detrimental aspects of chronic inflammation.

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Year:  1976        PMID： 178824      PMCID： PMC2190206          DOI： 10.1084/jem.143.6.1551

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  13 in total

1.  Antimicrobial mechanisms in neutrophilic polymorphonuclear leukocytes.

Authors:  S J Klebanoff
Journal:  Semin Hematol       Date:  1975-04       Impact factor: 3.851

2.  The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes.

Authors:  R B Johnston; B B Keele; H P Misra; J E Lehmeyer; L S Webb; R L Baehner; K V RaJagopalan
Journal:  J Clin Invest       Date:  1975-06       Impact factor: 14.808

3.  The role of superoxide anion and hydrogen peroxide in phagocytosis-associated oxidative metabolic reactions.

Authors:  R L Baehner; S K Murrmann; J Davis; R B Johnston
Journal:  J Clin Invest       Date:  1975-09       Impact factor: 14.808

4.  Elaboration of toxic oxygen by-products by neutrophils in a model of immune complex disease.

Authors:  R B Johnston; J E Lehmeyer
Journal:  J Clin Invest       Date:  1976-04       Impact factor: 14.808

5.  Metabolic and functional studies of monocytes in congenital neutropenia.

Authors:  W D Biggar; B Holmes; A R Page; A S Deinard; P L'Esperance; R A Good
Journal:  Br J Haematol       Date:  1974-10       Impact factor: 6.998

6.  Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent.

Authors:  B M Babior; R S Kipnes; J T Curnutte
Journal:  J Clin Invest       Date:  1973-03       Impact factor: 14.808

7.  Peroxidative metabolism in alveolar macrophages.

Authors:  J B Gee; C L Vassallo; M T Vogt; C Thomas; R E Basford
Journal:  Arch Intern Med       Date:  1971-06

8.  Phagocytosis by human monocytes.

Authors:  M J Cline; R I Lehrer
Journal:  Blood       Date:  1968-09       Impact factor: 22.113

9.  Monocyte function in children with neutropenia and chronic infections.

Authors:  R L Baehner; R B Johnston
Journal:  Blood       Date:  1972-07       Impact factor: 22.113

10.  Evidence for the generation of an electronic excitation state(s) in human polymorphonuclear leukocytes and its participation in bactericidal activity.

Authors:  R C Allen; R L Stjernholm; R H Steele
Journal:  Biochem Biophys Res Commun       Date:  1972-05-26       Impact factor: 3.575
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  71 in total

1.  Inflammatory mediators in dengue virus infection in children: interleukin-8 and its relationship to neutrophil degranulation.

Authors:  M Juffrie; G M van Der Meer; C E Hack; K Haasnoot; A J Veerman; L G Thijs
Journal:  Infect Immun       Date:  2000-02       Impact factor: 3.441

Review 2.  Mechanisms of oxidant-induced changes in erythrocytes.

Authors:  J R Hatherill; G O Till; P A Ward
Journal:  Agents Actions       Date:  1991-03

3.  Increased superoxide anion production by immunologically activated and chemically elicited macrophages.

Authors:  R B Johnston; C A Godzik; Z A Cohn
Journal:  J Exp Med       Date:  1978-07-01       Impact factor: 14.307

4.  The effect of phorbol myristate acetate on the metabolism and ultrastructure of human alveolar macrophages.

Authors:  J R Hoidal; J E Repine; G D Beall; F L Rasp; J G White
Journal:  Am J Pathol       Date:  1978-06       Impact factor: 4.307

5.  Differences in oxygen metabolism of phagocytosing monocytes and neutrophils.

Authors:  M Reiss; D Roos
Journal:  J Clin Invest       Date:  1978-02       Impact factor: 14.808

6.  Intracellular hydrogen peroxide production by peripheral phagocytes from diabetic patients. Dissociation between polymorphonuclear leucocytes and monocytes.

Authors:  M Noritake; Y Katsura; N Shinomiya; M Kanatani; Y Uwabe; N Nagata; S Tsuru
Journal:  Clin Exp Immunol       Date:  1992-05       Impact factor: 4.330

7.  IgG and IgA enhance the chrysotile-induced production of reactive oxygen metabolites by human polymorphonuclear leucocytes.

Authors:  M Klockars; M Hedenborg; J Koistinen; T Isobe
Journal:  Clin Exp Immunol       Date:  1989-12       Impact factor: 4.330

8.  Heparin binding protein (CAP37) is an opsonin for Staphylococcus aureus and increases phagocytosis in monocytes.

Authors:  M Heinzelmann; A Platz; H Flodgaard; F N Miller
Journal:  Inflammation       Date:  1998-10       Impact factor: 4.092

9.  Monocyte superoxide anion production in rheumatoid arthritis: preliminary evidence for enhanced rates of superoxide anion production by monocytes from patients receiving penicillamine, sodium aurothiomalate and corticosteroids.

Authors:  N P Hurst; B Bessac; G Nuki
Journal:  Ann Rheum Dis       Date:  1984-02       Impact factor: 19.103

10.  Requirement of extracellular complement and immunoglobulin for intracellular killing of micro-organisms by human monocytes.

Authors:  P C Leijh; M T van den Barselaar; T L van Zwet; M R Daha; R van Furth
Journal:  J Clin Invest       Date:  1979-04       Impact factor: 14.808
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