Literature DB >> 18783174

Reverse engineering models of cell cycle regulation.

Attila Csikász-Nagy1, Béla Novák, John J Tyson.   

Abstract

From general considerations of the basic physiological properties of the cell division cycle, we deduce what the dynamical properties of the underlying molecular control system must be. Then, taking a few hints from the biochemistry of cyclin-dependent kinases (the master regulators of the eukaryotic cell cycle), we guess what molecular mechanisms must be operating to produce the desired dynamical properties of the control system.

Mesh：

Year:  2008        PMID： 18783174     DOI： 10.1007/978-0-387-09794-7_7

Source DB:  PubMed          Journal:  Adv Exp Med Biol        ISSN： 0065-2598            Impact factor:   2.622


  5 in total

1.  Dynamics in hybrid complex systems of switches and oscillators.

Authors:  Dane Taylor; Elana J Fertig; Juan G Restrepo
Journal:  Chaos       Date:  2013-09       Impact factor: 3.642

Review 2.  Pattern, growth, and control.

Authors:  Arthur D Lander
Journal:  Cell       Date:  2011-03-18       Impact factor: 41.582

3.  Mathematical modeling of fission yeast Schizosaccharomyces pombe cell cycle: exploring the role of multiple phosphatases.

Authors:  P Anbumathi; Sharad Bhartiya; K V Venkatesh
Journal:  Syst Synth Biol       Date:  2011-12-08

4.  Quantifying the dynamics of coupled networks of switches and oscillators.

Authors:  Matthew R Francis; Elana J Fertig
Journal:  PLoS One       Date:  2012-01-05       Impact factor: 3.240

5.  Boolean network model predicts knockout mutant phenotypes of fission yeast.

Authors:  Maria I Davidich; Stefan Bornholdt
Journal:  PLoS One       Date:  2013-09-19       Impact factor: 3.240
  5 in total

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