Literature DB >> 18781661

Extinction retention predicts improvement in social anxiety symptoms following exposure therapy.

Angela C Berry1, David Rosenfield, Jasper A J Smits.   

Abstract

BACKGROUND: Several researchers have argued that basic research on extinction learning can guide efforts to enhance the efficacy of exposure-based therapy. At the basis of this translational research paradigm is the assumption that extinction retention is important to the outcome of exposure-based therapy. This study is the first to examine the relationship between extinction retention, which comprises the amount of fear reduction that is retained between two exposure sessions and improvement in anxiety symptoms following exposure treatment.
METHODS: Adults (N=90), participating in two separate studies, who received three sessions of repeated exposure to public speaking provided ratings of peak fear during exposure treatment and completed the Liebowitz Social Anxiety Scale Self-Report version, LSAS-SR, Baker et al. [2002: Behav Res Ther 40:701-715] at baseline, posttreatment, and follow-up.
RESULTS: After controlling for within-session extinction, extinction retention accounted for significant variance in the improvement of LSAS-SR scores over time.
CONCLUSIONS: Our findings suggest that the consolidation of extinction learning into long-term memory is associated with improvements in fear and avoidance related to social situations following exposure therapy. Implications for exposure therapy augmentation studies are discussed.

Entities:  

Mesh:

Year:  2009        PMID: 18781661     DOI: 10.1002/da.20511

Source DB:  PubMed          Journal:  Depress Anxiety        ISSN: 1091-4269            Impact factor:   6.505


  12 in total

1.  Brain structure correlates of individual differences in the acquisition and inhibition of conditioned fear.

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2.  Enhancing panic and smoking reduction treatment with D-Cycloserine: A pilot randomized clinical trial.

Authors:  Jasper A J Smits; Michael J Zvolensky; Michael W Otto; Megan E Piper; Scarlett O Baird; Brooke Y Kauffman; Eunjung Lee-Furman; Noura Alavi; Christina D Dutcher; Santiago Papini; Benjamin Rosenfield; David Rosenfield
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3.  Serotonin transporter polyadenylation polymorphism modulates the retention of fear extinction memory.

Authors:  Catherine A Hartley; Morgan C McKenna; Rabia Salman; Andrew Holmes; B J Casey; Elizabeth A Phelps; Charles E Glatt
Journal:  Proc Natl Acad Sci U S A       Date:  2012-03-19       Impact factor: 11.205

Review 4.  The role of stress and fear in the development of mental disorders.

Authors:  Polaris Gonzalez; Karen G Martinez
Journal:  Psychiatr Clin North Am       Date:  2014-10-11

5.  Exercise Augmentation of Exposure Therapy for PTSD: Rationale and Pilot Efficacy Data.

Authors:  Mark B Powers; Johnna L Medina; Stephanie Burns; Brooke Y Kauffman; Marie Monfils; Gordon J G Asmundson; Allison Diamond; Christa McIntyre; Jasper A J Smits
Journal:  Cogn Behav Ther       Date:  2015-02-23

6.  Transcranial direct current stimulation targeting the medial prefrontal cortex modulates functional connectivity and enhances safety learning in obsessive-compulsive disorder: Results from two pilot studies.

Authors:  Thomas G Adams; Josh M Cisler; Benjamin Kelmendi; Jamilah R George; Stephen A Kichuk; Christopher L Averill; Alan Anticevic; Chadi G Abdallah; Christopher Pittenger
Journal:  Depress Anxiety       Date:  2021-08-31       Impact factor: 6.505

7.  D-Cycloserine as an augmentation strategy with cognitive-behavioral therapy for social anxiety disorder.

Authors:  Stefan G Hofmann; Jasper A J Smits; David Rosenfield; Naomi Simon; Michael W Otto; Alicia E Meuret; Luana Marques; Angela Fang; Candyce Tart; Mark H Pollack
Journal:  Am J Psychiatry       Date:  2013-07       Impact factor: 18.112

8.  D-cycloserine enhancement of exposure therapy for social anxiety disorder depends on the success of exposure sessions.

Authors:  Jasper A J Smits; David Rosenfield; Michael W Otto; Luana Marques; Michelle L Davis; Alicia E Meuret; Naomi M Simon; Mark H Pollack; Stefan G Hofmann
Journal:  J Psychiatr Res       Date:  2013-07-16       Impact factor: 4.791

9.  Risk for anxiety and implications for treatment: developmental, environmental, and genetic factors governing fear regulation.

Authors:  Catherine A Hartley; B J Casey
Journal:  Ann N Y Acad Sci       Date:  2013-10-22       Impact factor: 5.691

10.  Internet-based attention bias modification for social anxiety: a randomised controlled comparison of training towards negative and training towards positive cues.

Authors:  Johanna Boettcher; Linda Leek; Lisa Matson; Emily A Holmes; Michael Browning; Colin MacLeod; Gerhard Andersson; Per Carlbring
Journal:  PLoS One       Date:  2013-09-30       Impact factor: 3.240

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