Literature DB >> 18780806

Medication reconciliation at hospital discharge: evaluating discrepancies.

Jacqueline D Wong1, Jana M Bajcar, Gary G Wong, Shabbir M H Alibhai, Jin-Hyeun Huh, Annemarie Cesta, Gregory R Pond, Olavo A Fernandes.   

Abstract

BACKGROUND: Hospital discharge is an interface of care when patients are at a high risk of medication discrepancies as they transition from hospital to home. These discrepancies are important, as they may contribute to drug-related problems, medication errors, and adverse drug events.
OBJECTIVE: To identify, characterize, and assess the clinical impact of unintentional medication discrepancies at hospital discharge.
METHODS: All consecutive general internal medicine patients admitted for at least 72 hours to a tertiary care teaching hospital were prospectively assessed. Patients were excluded if they were discharged with verbal prescriptions; died during hospitalization; or transferred from or to a nursing home, another institution, or another unit within the same hospital. The primary endpoint was to determine the number of patients with at least one unintended medication discrepancy on hospital discharge. Medication discrepancies were assessed through comparison of a best possible medication discharge list with the actual discharge prescriptions. Secondary objectives were to characterize and assess the potential clinical impact of the unintentional discrepancies.
RESULTS: From March 14, 2006, to June 2, 2006, 430 patients were screened for eligibility; 150 patients were included in the study. Overall, 106 (70.7%) patients had at least one actual or potential unintentional discrepancy. Sixty-two patients (41.3%) had at least one actual unintentional medication discrepancy at hospital discharge and 83 patients (55.3%) had at least one potential unintentional discrepancy. The most common unintentional discrepancies were an incomplete prescription requiring clarification, which could result in a patient delay in obtaining medications (49.5%), and the omission of medications (22.9%). Of the 105 unintentional discrepancies, 31(29.5%) had the potential to cause possible or probable patient discomfort and/or clinical deterioration.
CONCLUSIONS: Medication discrepancies occur commonly on hospital discharge. Understanding the type and frequency of discrepancies can help clinicians better understand ways to prevent them. Structured medication reconciliation may help to prevent discharge medication discrepancies.

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Year:  2008        PMID: 18780806     DOI: 10.1345/aph.1L190

Source DB:  PubMed          Journal:  Ann Pharmacother        ISSN: 1060-0280            Impact factor:   3.154


  83 in total

1.  Pharmacists' interventions in prescribing errors at hospital discharge: an observational study in the context of an electronic prescribing system in a UK teaching hospital.

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2.  Role of the Pharmacist in Caring for Patients with HIV/AIDS: Clinical Practice Guidelines.

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Journal:  Can J Hosp Pharm       Date:  2012-03

3.  Effect of Misalignment between Hospital and Provincial Formularies on Medication Discrepancies at Discharge: PPITS (Proton Pump Inhibitor Therapeutic Substitution) Study.

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4.  Analysis of medication information exchange at discharge from a Dutch hospital.

Authors:  Inge R F van Berlo-van de Laar; Erwin Driessen; Maria M Merkx; Frank G A Jansman
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Review 6.  Tools for Assessing Potential Significance of Pharmacist Interventions: A Systematic Review.

Authors:  Thi-Ha Vo; Bruno Charpiat; Claire Catoire; Michel Juste; Renaud Roubille; François-Xavier Rose; Sébastien Chanoine; Jean-Luc Bosson; Ornella Conort; Benoît Allenet; Pierrick Bedouch
Journal:  Drug Saf       Date:  2016-02       Impact factor: 5.606

7.  Safe Medication Reconciliation: An Intervention to Improve Residents' Medication Reconciliation Skills.

Authors:  Cherinne Arundel; Jessica Logan; Ribka Ayana; Jacqueline Gannuscio; Jennifer Kerns; Rebecca Swenson
Journal:  J Grad Med Educ       Date:  2015-09

Review 8.  Initiatives promoting seamless care in medication management: an international review of the grey literature.

Authors:  Coraline Claeys; Veerle Foulon; Sabrina de Winter; Anne Spinewine
Journal:  Int J Clin Pharm       Date:  2013-12

9.  Medication discrepancies upon hospital to skilled nursing facility transitions.

Authors:  Jennifer Tjia; Alice Bonner; Becky A Briesacher; Sarah McGee; Eileen Terrill; Kathleen Miller
Journal:  J Gen Intern Med       Date:  2009-03-17       Impact factor: 5.128

10.  Pharmacist's Role in Improving Medication Safety for Patients in an Allogeneic Hematopoietic Cell Transplant Ambulatory Clinic.

Authors:  Lina Ho; Keith Akada; Hans Messner; John Kuruvilla; Janice Wright; Jack T Seki
Journal:  Can J Hosp Pharm       Date:  2013-03
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