Literature DB >> 18779805

Data completeness--the Achilles heel of drug-target networks.

Jordi Mestres, Elisabet Gregori-Puigjané, Sergi Valverde, Ricard V Solé.   

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Year:  2008        PMID： 18779805     DOI： 10.1038/nbt0908-983

Source DB:  PubMed          Journal:  Nat Biotechnol        ISSN： 1087-0156            Impact factor:   54.908


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  83 in total

1.  Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing.

Authors:  Tudor I Oprea; Sonny Kim Nielsen; Oleg Ursu; Jeremy J Yang; Olivier Taboureau; Stephen L Mathias; Lrene Kouskoumvekaki; Larry A Sklar; Cristian G Bologa
Journal:  Mol Inform       Date:  2011-03-14       Impact factor: 3.353

2.  PDID: database of molecular-level putative protein-drug interactions in the structural human proteome.

Authors:  Chen Wang; Gang Hu; Kui Wang; Michal Brylinski; Lei Xie; Lukasz Kurgan
Journal:  Bioinformatics       Date:  2015-10-26       Impact factor: 6.937

Review 3.  The human endogenous metabolome as a pharmacology baseline for drug discovery.

Authors:  Andreu Bofill; Xavier Jalencas; Tudor I Oprea; Jordi Mestres
Journal:  Drug Discov Today       Date:  2019-06-19       Impact factor: 7.851

Review 4.  From laptop to benchtop to bedside: structure-based drug design on protein targets.

Authors:  Lu Chen; John K Morrow; Hoang T Tran; Sharangdhar S Phatak; Lei Du-Cuny; Shuxing Zhang
Journal:  Curr Pharm Des       Date:  2012       Impact factor: 3.116

5.  A structural chemogenomics analysis of aminergic GPCRs: lessons for histamine receptor ligand design.

Authors:  A J Kooistra; S Kuhne; I J P de Esch; R Leurs; C de Graaf
Journal:  Br J Pharmacol       Date:  2013-09       Impact factor: 8.739

6.  Systematic analysis of gene properties influencing organ system phenotypes in mammalian perturbations.

Authors:  Ingo Vogt; Jeanette Prinz; Karolina Worf; Monica Campillos
Journal:  Bioinformatics       Date:  2014-07-23       Impact factor: 6.937

7.  Statistical structure of host-phage interactions.

Authors:  Cesar O Flores; Justin R Meyer; Sergi Valverde; Lauren Farr; Joshua S Weitz
Journal:  Proc Natl Acad Sci U S A       Date:  2011-06-27       Impact factor: 11.205

8.  Navigating the kinome.

Authors:  James T Metz; Eric F Johnson; Niru B Soni; Philip J Merta; Lemma Kifle; Philip J Hajduk
Journal:  Nat Chem Biol       Date:  2011-02-20       Impact factor: 15.040

9.  Shaping the future of safer innovative drugs in Europe.

Authors:  Jordi Mestres; Sharon D Bryant; Ismael Zamora; Johann Gasteiger
Journal:  Nat Biotechnol       Date:  2011-09-08       Impact factor: 54.908

10.  A survey of across-target bioactivity results of small molecules in PubChem.

Authors:  Lianyi Han; Yanli Wang; Stephen H Bryant
Journal:  Bioinformatics       Date:  2009-06-23       Impact factor: 6.937
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