Literature DB >> 18779528

The "number needed to treat" turns 20--and continues to be used and misused.

Finlay A McAlister1.   

Abstract

Mesh:

Year:  2008        PMID: 18779528      PMCID: PMC2527399          DOI: 10.1503/cmaj.080484

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


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  44 in total

Review 1.  The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomized trials.

Authors:  D Moher; K F Schulz; D Altman
Journal:  JAMA       Date:  2001-04-18       Impact factor: 56.272

Review 2.  Shifts in mortality curves: saving or extending lives? .

Authors:  L B Tan; R Murphy
Journal:  Lancet       Date:  1999-10-16       Impact factor: 79.321

3.  Commentary: relative treatment effects are consistent across the spectrum of underlying risks...usually.

Authors:  Finlay A McAlister
Journal:  Int J Epidemiol       Date:  2002-02       Impact factor: 7.196

4.  Comparing medications in a therapeutic area using an NNT model.

Authors:  J Jaime Caro; K Jack Ishak; Ingrid Caro; Kristen Migliaccio-Walle; Wendy S Klittich
Journal:  Value Health       Date:  2004 Sep-Oct       Impact factor: 5.725

5.  Absolutely relative: how research results are summarized can affect treatment decisions.

Authors:  L Forrow; W C Taylor; R M Arnold
Journal:  Am J Med       Date:  1992-02       Impact factor: 4.965

Review 6.  Number-needed-to-treat (NNT)--needs treatment with care.

Authors:  Palle Mark Christensen; Ivar Sønbø Kristiansen
Journal:  Basic Clin Pharmacol Toxicol       Date:  2006-07       Impact factor: 4.080

7.  Effect of antihypertensive drug treatment on cardiovascular outcomes in women and men. A meta-analysis of individual patient data from randomized, controlled trials. The INDANA Investigators.

Authors:  F Gueyffier; F Boutitie; J P Boissel; S Pocock; J Coope; J Cutler; T Ekbom; R Fagard; L Friedman; M Perry; R Prineas; E Schron
Journal:  Ann Intern Med       Date:  1997-05-15       Impact factor: 25.391

8.  A randomized comparison of patients' understanding of number needed to treat and other common risk reduction formats.

Authors:  Stacey L Sheridan; Michael P Pignone; Carmen L Lewis
Journal:  J Gen Intern Med       Date:  2003-11       Impact factor: 5.128

9.  Measured enthusiasm: does the method of reporting trial results alter perceptions of therapeutic effectiveness?

Authors:  C D Naylor; E Chen; B Strauss
Journal:  Ann Intern Med       Date:  1992-12-01       Impact factor: 25.391

10.  Does random treatment assignment cause harm to research participants?

Authors:  Cary P Gross; Harlan M Krumholz; Gretchen Van Wye; Ezekiel J Emanuel; David Wendler
Journal:  PLoS Med       Date:  2006-06       Impact factor: 11.069

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  18 in total

1.  Number needed to treat and baseline risks.

Authors:  James P McCormack
Journal:  CMAJ       Date:  2008-11-18       Impact factor: 8.262

Review 2.  Efficacy of statins for primary prevention in people at low cardiovascular risk: a meta-analysis.

Authors:  Marcello Tonelli; Anita Lloyd; Fiona Clement; Jon Conly; Don Husereau; Brenda Hemmelgarn; Scott Klarenbach; Finlay A McAlister; Natasha Wiebe; Braden Manns
Journal:  CMAJ       Date:  2011-10-11       Impact factor: 8.262

3.  Augmented Reality.

Authors:  M K O'Reilly; P J Heagerty; L S Gold; D F Kallmes; J G Jarvik
Journal:  AJNR Am J Neuroradiol       Date:  2020-07-16       Impact factor: 3.825

4.  The "1-year-death number needed to treat" for comparing the impact of distinct interventions on patient outcomes.

Authors:  Brett N Hryciw; Finlay A McAlister; Meltem Tuna; Carl van Walraven
Journal:  CMAJ       Date:  2019-11-11       Impact factor: 8.262

5.  Uses and misuses of statistics: the case of strontium ranelate and the number needed to treat.

Authors:  M Pedrazzoni; A Giusti; G Pioli
Journal:  J Endocrinol Invest       Date:  2011-09       Impact factor: 4.256

6.  Using and Interpreting Adjusted NNT Measures in Biomedical Research.

Authors:  Ralf Bender
Journal:  Open Dent J       Date:  2010-07-16

7.  CHEMOPROPHYLAXIS TO CONTROL LEPROSY AND THE PERSPECTIVE OF ITS IMPLEMENTATION IN BRAZIL: A PRIMER FOR NON-EPIDEMIOLOGISTS.

Authors:  Sergio Souza da Cunha; Ana Luiza Bierrenbach; Vitor Hugo Lima Barreto
Journal:  Rev Inst Med Trop Sao Paulo       Date:  2015-12       Impact factor: 1.846

8.  Does Hospital Admission/Observation for Chest Pain Improve Patient Outcomes after Emergency Department Evaluation for Suspected Acute Coronary Syndrome?

Authors:  Adam L Sharp; Aniket A Kawatkar; Aileen S Baecker; Rita F Redberg; Ming-Sum Lee; Maros Ferencik; Yi-Lin Wu; Ernest Shen; Chengyi Zheng; Stacy Park; Steve Goodacre; Praveen Thokala; Benjamin C Sun
Journal:  J Gen Intern Med       Date:  2021-05-14       Impact factor: 5.128

9.  Quantifying the impact of community quarantine on SARS transmission in Ontario: estimation of secondary case count difference and number needed to quarantine.

Authors:  Susan J Bondy; Margaret L Russell; Julie Ml Laflèche; Elizabeth Rea
Journal:  BMC Public Health       Date:  2009-12-24       Impact factor: 3.295

10.  The Number Needed to Treat: 25 Years of Trials and Tribulations in Clinical Research.

Authors:  Samy Suissa
Journal:  Rambam Maimonides Med J       Date:  2015-07-30
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