| Literature DB >> 18776494 |
Victor E Marquez1, Guangyu Sun, Maqbool A Siddiqui, Yi-Chien Lee, Joseph J Barchi, Igor V Filippov, Nicklaus A Landsman, James A Kelley.
Abstract
The consequences of freezing the orientation of the oxygen's lone pair orbitals--which determines whether the anomeric effect is operative or not--were studied theoretically and experimentally in two oxobicyclo-[3.1.0]hexane nucleosides (1 and 2). The results showed significant differences in the properties of these molecules, which correlated with the magnitude of the n2 --> sigma * delocalization.Entities:
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Year: 2008 PMID： 18776494 PMCID： PMC2700545 DOI： 10.1093/nass/nrn275
Source DB: PubMed Journal: Nucleic Acids Symp Ser (Oxf) ISSN： 0261-3166