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Literature DB >> 18772425

An enzyme assembly line

Janet L Smith¹, David H Sherman.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2008 PMID： 18772425 PMCID： PMC2936446 DOI： 10.1126/science.1163785

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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12 in total

1. The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.

Authors: Yinyan Tang; Chu-Young Kim; Irimpan I Mathews; David E Cane; Chaitan Khosla
Journal: Proc Natl Acad Sci U S A Date: 2006-07-14 Impact factor: 11.205

2. GNAT-like strategy for polyketide chain initiation.

Authors: Liangcai Gu; Todd W Geders; Bo Wang; William H Gerwick; Kristina Håkansson; Janet L Smith; David H Sherman
Journal: Science Date: 2007-11-09 Impact factor: 47.728

3. Architecture of a fungal fatty acid synthase at 5 A resolution.

Authors: Simon Jenni; Marc Leibundgut; Timm Maier; Nenad Ban
Journal: Science Date: 2006-03-03 Impact factor: 47.728

4. The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases.

Authors: Adrian T Keatinge-Clay; Robert M Stroud
Journal: Structure Date: 2006-03-23 Impact factor: 5.006

Review 5. Versatile polyketide enzymatic machinery for the biosynthesis of complex mycobacterial lipids.

Authors: Rajesh S Gokhale; Priti Saxena; Tarun Chopra; Debasisa Mohanty
Journal: Nat Prod Rep Date: 2007-02-28 Impact factor: 13.423

6. Escherichia coli induces DNA double-strand breaks in eukaryotic cells.

Authors: Jean-Philippe Nougayrède; Stefan Homburg; Frédéric Taieb; Michèle Boury; Elzbieta Brzuszkiewicz; Gerhard Gottschalk; Carmen Buchrieser; Jörg Hacker; Ulrich Dobrindt; Eric Oswald
Journal: Science Date: 2006-08-11 Impact factor: 47.728

7. Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula.

Authors: Zunxue Chang; Namthip Sitachitta; James V Rossi; Mary Ann Roberts; Patricia M Flatt; Junyong Jia; David H Sherman; William H Gerwick
Journal: J Nat Prod Date: 2004-08 Impact factor: 4.050

8. Architecture of mammalian fatty acid synthase at 4.5 A resolution.

Authors: Timm Maier; Simon Jenni; Nenad Ban
Journal: Science Date: 2006-03-03 Impact factor: 47.728

9. The crystal structure of a mammalian fatty acid synthase.

Authors: Timm Maier; Marc Leibundgut; Nenad Ban
Journal: Science Date: 2008-09-05 Impact factor: 47.728

10. The origins of specificity in polyketide synthase protein interactions.

Authors: Mukund Thattai; Yoram Burak; Boris I Shraiman
Journal: PLoS Comput Biol Date: 2007-09 Impact factor: 4.475

19 in total

1. Unique actinomycetes from marine caves and coral reef sediments provide novel PKS and NRPS biosynthetic gene clusters.

Authors: Tyler W Hodges; Marc Slattery; Julie B Olson
Journal: Mar Biotechnol (NY) Date: 2011-10-15 Impact factor: 3.619

2. Reconstitution of the FK228 biosynthetic pathway reveals cross talk between modular polyketide synthases and fatty acid synthase.

Authors: Shane R Wesener; Vishwakanth Y Potharla; Yi-Qiang Cheng
Journal: Appl Environ Microbiol Date: 2010-12-23 Impact factor: 4.792

An enzyme assembly line

1. The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase.

2. GNAT-like strategy for polyketide chain initiation.

3. Architecture of a fungal fatty acid synthase at 5 A resolution.

4. The structure of a ketoreductase determines the organization of the beta-carbon processing enzymes of modular polyketide synthases.

Review 5. Versatile polyketide enzymatic machinery for the biosynthesis of complex mycobacterial lipids.

6. Escherichia coli induces DNA double-strand breaks in eukaryotic cells.

7. Biosynthetic pathway and gene cluster analysis of curacin A, an antitubulin natural product from the tropical marine cyanobacterium Lyngbya majuscula.

8. Architecture of mammalian fatty acid synthase at 4.5 A resolution.

9. The crystal structure of a mammalian fatty acid synthase.

10. The origins of specificity in polyketide synthase protein interactions.

1. Unique actinomycetes from marine caves and coral reef sediments provide novel PKS and NRPS biosynthetic gene clusters.

2. Reconstitution of the FK228 biosynthetic pathway reveals cross talk between modular polyketide synthases and fatty acid synthase.

Review 3. Fatty acid biosynthesis in actinomycetes.

4. Functional Characterization of a Dehydratase Domain from the Pikromycin Polyketide Synthase.

5. Crystal structures of dehydratase domains from the curacin polyketide biosynthetic pathway.

Review 6. Structural analysis of protein-protein interactions in type I polyketide synthases.

7. Metamorphic enzyme assembly in polyketide diversification.

8. Bacterial fatty acid synthesis and its relationships with polyketide synthetic pathways.

9. Non-Catalytic Subunits Facilitate Quaternary Organization of Plastidic Acetyl-CoA Carboxylase.

Review 10. Diversity in enoyl-acyl carrier protein reductases.