Literature DB >> 18771270

Synephrine content of juice from Satsuma mandarins (Citrus unshiu Marcovitch).

Klaus Dragull1, Andrew P Breksa, Brian Cain.   

Abstract

Synephrine, the main protoalkaloid in Citrus species, is commonly analyzed as the active component in citrus peel-containing herbal supplements, but the edible parts of mandarins have been largely ignored. The synephrine concentration has been determined in the juices of Citrus unshiu mandarins harvested from 10 different groves located in a major growing region in California. For comparison, the physicochemical properties of the juices, including pH, conductivity, soluble solids content, and titratable acidity, were also measured. The synephrine values among 10 groves ranged from 73.3 to 158.1 mg L (-1). Repeat sampling of fruit from the 10 locations showed that the intragrove variability in synephrine concentrations ranged from 1.0 to 27.7% CV and was grove dependent. Among the physicochemical properties, titratable acidity weakly correlated with synephrine, and for one sample a low maturity index was linked to high synephrine content. The overall mean synephrine concentration of 92.8 mg L (-1) is up to 6-fold higher than values previously determined for orange juices and suggests that mandarin juice could constitute a significant dietary source of synephrine. Furthermore, the results suggest that grove location and maturity affect synephrine content.

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Year:  2008        PMID: 18771270     DOI: 10.1021/jf801225n

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN: 0021-8561            Impact factor:   5.279


  11 in total

1.  Problems with Citrus aurantium information in "A review on botanical species and chemical compounds with appetite suppressing properties for body weight control".

Authors:  Sidney J Stohs
Journal:  Plant Foods Hum Nutr       Date:  2013-09       Impact factor: 3.921

2.  Isopropylnorsynephrine is a stronger lipolytic agent in human adipocytes than synephrine and other amines present in Citrus aurantium.

Authors:  Josep Mercader; Estelle Wanecq; Jian Chen; Christian Carpéné
Journal:  J Physiol Biochem       Date:  2011-02-19       Impact factor: 4.158

3.  Acute p-synephrine ingestion increases fat oxidation rate during exercise.

Authors:  Jorge Gutiérrez-Hellín; Juan Del Coso
Journal:  Br J Clin Pharmacol       Date:  2016-05-07       Impact factor: 4.335

Review 4.  A review of the human clinical studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine.

Authors:  Sidney J Stohs; Harry G Preuss; Mohd Shara
Journal:  Int J Med Sci       Date:  2012-08-29       Impact factor: 3.738

5.  Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes.

Authors:  Sidney J Stohs; Harry G Preuss; Samuel C Keith; Patti L Keith; Howard Miller; Gilbert R Kaats
Journal:  Int J Med Sci       Date:  2011-04-28       Impact factor: 3.738

Review 6.  A review of the receptor-binding properties of p-synephrine as related to its pharmacological effects.

Authors:  Sidney J Stohs; Harry G Preuss; Mohd Shara
Journal:  Oxid Med Cell Longev       Date:  2011-08-01       Impact factor: 6.543

7.  Unsupported conclusions in the article "Synephrine-containing dietary supplement precipitating apical ballooning syndrome in a young female".

Authors:  Sidney J Stohs
Journal:  Korean J Intern Med       Date:  2014-04-29       Impact factor: 2.884

Review 8.  Safety, Efficacy, and Mechanistic Studies Regarding Citrus aurantium (Bitter Orange) Extract and p-Synephrine.

Authors:  Sidney J Stohs
Journal:  Phytother Res       Date:  2017-07-28       Impact factor: 5.878

9.  Study to Probe Subsistence of Host-Guest Inclusion Complexes of α and β-Cyclodextrins with Biologically Potent Drugs for Safety Regulatory Dischargement.

Authors:  Biplab Rajbanshi; Subhadeep Saha; Koyeli Das; Biraj Kumar Barman; Swarnab Sengupta; Arindam Bhattacharjee; Mahendra Nath Roy
Journal:  Sci Rep       Date:  2018-08-29       Impact factor: 4.379

Review 10.  Plant natural products as an anti-lipid droplets accumulation agent.

Authors:  Chin Piow Wong; Toshio Kaneda; Hiroshi Morita
Journal:  J Nat Med       Date:  2014-02-19       Impact factor: 2.343

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