A microscopic study of increased vascular permeability and leucocyte emigration in thermal injury in the chicken skin.

Microscopic study of the acute inflammatory reaction following thermal injury in the chicken skin, using the colloidal carbon technique, revealed an increase in vascular permeability both in capillaries and venules. The capillary response was of a shorter duration than the venular response which was prolonged. Venular leakage seemed to play the major role in oedema formation. Concurrent emigration of heterophils and monocytes, and participation of basophil leucocytes in the early stages appeared to be the contrasting features from mammalian inflammation.