Gregory J Tranah1, Paige M Bracci, Elizabeth A Holly. 1. California Pacific Medical Center Research Institute, San Francisco Coordinating Center, University of California-San Francisco, San Francisco, CA 94107-1728, USA. gtranah@psg.ucsf.edu
Abstract
OBJECTIVE: To assess the association between animal exposures and non-Hodgkin's lymphoma (NHL). METHODS: Exposure data were collected from 1,591 cases and 2,515 controls during in-person interviews in a population-based case-control study of NHL in the San Francisco Bay Area. Odds ratios (OR) and 95% confidence intervals (95% CI) were adjusted for potential confounders. RESULTS: Pet owners had a reduced risk of NHL (OR, 0.71; 95% CI, 0.52-0.97) and diffuse large-cell lymphoma large cell (DLCL; OR, 0.58; 95% CI, 0.39-0.87) compared with those who never had owned a pet. Ever having owned dogs and/or cats was associated with reduced risk of all NHL (OR, 0.71; 95% CI, 0.54-0.94) and of DLCL (OR, 0.60; 95% CI, 0.42-0.86). Longer duration of cat ownership (P(trend) = 0.008), dog ownership (P(trend) = 0.04), and dog and/or cat ownership (P(trend) = 0.004) was inversely associated with risk of NHL. Ownership of pets other than cats and dogs was associated with a reduced risk of NHL (OR, 0.64; 95% CI, 0.55-0.74) and DLCL (OR, 0.58; 95% CI, 0.47-0.71). Exposure to cattle for >or=5 years was associated with an increased risk of NHL (OR, 1.6; 95% CI, 1.0-2.5) as was exposure to pigs for all NHL (OR, 1.8; 95% CI, 1.2-2.6) and for DLCL (OR, 2.0; 95% CI, 1.2-3.4). CONCLUSIONS: The association between animal exposure and NHL warrants further investigation in pooled analyses.
OBJECTIVE: To assess the association between animal exposures and non-Hodgkin's lymphoma (NHL). METHODS: Exposure data were collected from 1,591 cases and 2,515 controls during in-person interviews in a population-based case-control study of NHL in the San Francisco Bay Area. Odds ratios (OR) and 95% confidence intervals (95% CI) were adjusted for potential confounders. RESULTS: Pet owners had a reduced risk of NHL (OR, 0.71; 95% CI, 0.52-0.97) and diffuse large-cell lymphoma large cell (DLCL; OR, 0.58; 95% CI, 0.39-0.87) compared with those who never had owned a pet. Ever having owned dogs and/or cats was associated with reduced risk of all NHL (OR, 0.71; 95% CI, 0.54-0.94) and of DLCL (OR, 0.60; 95% CI, 0.42-0.86). Longer duration of cat ownership (P(trend) = 0.008), dog ownership (P(trend) = 0.04), and dog and/or cat ownership (P(trend) = 0.004) was inversely associated with risk of NHL. Ownership of pets other than cats and dogs was associated with a reduced risk of NHL (OR, 0.64; 95% CI, 0.55-0.74) and DLCL (OR, 0.58; 95% CI, 0.47-0.71). Exposure to cattle for >or=5 years was associated with an increased risk of NHL (OR, 1.6; 95% CI, 1.0-2.5) as was exposure to pigs for all NHL (OR, 1.8; 95% CI, 1.2-2.6) and for DLCL (OR, 2.0; 95% CI, 1.2-3.4). CONCLUSIONS: The association between animal exposure and NHL warrants further investigation in pooled analyses.
Authors: K P Cantor; A Blair; G Everett; R Gibson; L F Burmeister; L M Brown; L Schuman; F R Dick Journal: Cancer Res Date: 1992-05-01 Impact factor: 12.701
Authors: D Amadori; O Nanni; F Falcini; A Saragoni; V Tison; A Callea; E Scarpi; M Ricci; N Riva; E Buiatti Journal: Occup Environ Med Date: 1995-06 Impact factor: 4.402
Authors: Laura E Beane Freeman; Anneclaire J Deroos; Stella Koutros; Aaron Blair; Mary H Ward; Michael Alavanja; Jane A Hoppin Journal: Cancer Causes Control Date: 2012-03-10 Impact factor: 2.506
Authors: Jun Wang; Wendy Cozen; Peter S Thorne; Kiros Berhane; James R Cerhan; Patricia Hartge; Mary H Ward; Anneclaire J De Roos; Richard K Severson; Lindsay M Morton; Leslie Bernstein; Martha S Linet; Joanne S Colt Journal: Cancer Causes Control Date: 2013-01-01 Impact factor: 2.506
Authors: David O Garcia; Eric M Lander; Betsy C Wertheim; JoAnn E Manson; Stella L Volpe; Rowan T Chlebowski; Marcia L Stefanick; Lawrence S Lessin; Lewis H Kuller; Cynthia A Thomson Journal: Cancer Epidemiol Biomarkers Prev Date: 2016-06-30 Impact factor: 4.254
Authors: R Dolcetti; D Serraino; G Dognini; S Govi; R Crocchiolo; P Ghia; E Pasini; M Ponzoni; R Talamini; P De Paoli; C Doglioni; A J M Ferreri Journal: Br J Cancer Date: 2012-01-24 Impact factor: 7.640
Authors: Martha G Rhoades; Jane L Meza; Cheryl L Beseler; Patrick J Shea; Andy Kahle; Julie M Vose; Kent M Eskridge; Roy F Spalding Journal: Environ Health Insights Date: 2013-03-03