GOALS: It is generally recommended to wait for at least 24 h before starting chemotherapy after implanting venous port catheters (VPC). Our aim was to evaluate whether it is safe to start chemotherapy on the day of implantation. PATIENTS AND METHODS: One hundred eighty patients who had to be given chemotherapy on the day of VPC implantation at our institution from June 2005 to April 2007 were included. MAIN RESULTS: Of patients, 122 were male (67.8%) and median age was 55 years. Majority (133, 72.8%) had colon and gastric adenocancer. Median time to chemotherapy onset from VPC implantation was 102 min (minimum-maximum, 12-402). One hundred sixty-four (91.1%) received prolonged chemotherapy infusions beyond 48 h. No life-threatening acute complications like pneumothorax and hemothorax developed. In one patient extravasation (empty saline extravasation secondary to wrong insertion of the needle), in 17 (9.4%) pain, and in 41 (22.8%) minor bleeding as echymosis were seen. Thrombosis developed in 11 (6.1%). Reasons for VPC removal were thrombosis (2), sepsis (2), cellulitis (1), skin dehiscence (1), and patient will (1). CONCLUSION: Chemotherapy administration immediately after VPC implantation appears safe without increased acute and chronic complications in inpatient setting.
GOALS: It is generally recommended to wait for at least 24 h before starting chemotherapy after implanting venous port catheters (VPC). Our aim was to evaluate whether it is safe to start chemotherapy on the day of implantation. PATIENTS AND METHODS: One hundred eighty patients who had to be given chemotherapy on the day of VPC implantation at our institution from June 2005 to April 2007 were included. MAIN RESULTS: Of patients, 122 were male (67.8%) and median age was 55 years. Majority (133, 72.8%) had colon and gastric adenocancer. Median time to chemotherapy onset from VPC implantation was 102 min (minimum-maximum, 12-402). One hundred sixty-four (91.1%) received prolonged chemotherapy infusions beyond 48 h. No life-threatening acute complications like pneumothorax and hemothorax developed. In one patient extravasation (empty saline extravasation secondary to wrong insertion of the needle), in 17 (9.4%) pain, and in 41 (22.8%) minor bleeding as echymosis were seen. Thrombosis developed in 11 (6.1%). Reasons for VPC removal were thrombosis (2), sepsis (2), cellulitis (1), skin dehiscence (1), and patient will (1). CONCLUSION: Chemotherapy administration immediately after VPC implantation appears safe without increased acute and chronic complications in inpatient setting.
Authors: E E Vokes; R L Schilsky; K E Choi; D M Magid; C M Guarnieri; S M Whaling; M J Ratain; R R Weichselbaum; W R Panje Journal: Cancer Date: 1989-01-01 Impact factor: 6.860
Authors: Christoph Harter; Hans Jürgen Salwender; Alfons Bach; Gerlinde Egerer; Hartmut Goldschmidt; Anthony D Ho Journal: Cancer Date: 2002-01-01 Impact factor: 6.860
Authors: Jo Caers; Christel Fontaine; Vincent Vinh-Hung; Johan De Mey; Gerrit Ponnet; Chris Oost; Jan Lamote; Jacques De Greve; Benjamin Van Camp; Patrick Lacor Journal: Support Care Cancer Date: 2004-11-05 Impact factor: 3.603
Authors: A F Sobrero; C Aschele; A P Guglielmi; A M Mori; L M Tixi; E A Bolli; R Rosso; S Mammoliti; G A Rollandi; S Bertoglio Journal: Clin Cancer Res Date: 1995-09 Impact factor: 12.531
Authors: J Vardy; K Engelhardt; K Cox; J Jacquet; A McDade; M Boyer; P Beale; M Stockler; R Loneragan; B Dennien; R Waugh; S J Clarke Journal: Br J Cancer Date: 2004-09-13 Impact factor: 7.640