Literature DB >> 18760288

Epigenetics of beta-globin gene regulation.

Christine M Kiefer1, Chunhui Hou, Jane A Little, Ann Dean.   

Abstract

It is widely recognized that the next great challenge in the post-genomic period is to understand how the genome establishes the cell and tissue specific patterns of gene expression that underlie development. The beta-globin genes are among the most extensively studied tissue specific and developmentally regulated genes. The onset of erythropoiesis in precursor cells and the progressive expression of different members of the beta-globin family during development are accompanied by dramatic epigenetic changes in the locus. In this review, we will consider the relationship between histone and DNA modifications and the transcriptional activity of the beta-globin genes, the dynamic changes in epigenetic modifications observed during erythroid development, and the potential these changes hold as new targets for therapy in human disease.

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Year:  2008        PMID： 18760288      PMCID： PMC2617773          DOI： 10.1016/j.mrfmmm.2008.07.014

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  94 in total

Review 1.  An epigenetic road map for histone lysine methylation.

Authors:  Monika Lachner; Roderick J O'Sullivan; Thomas Jenuwein
Journal:  J Cell Sci       Date:  2003-06-01       Impact factor: 5.285

2.  Looping and interaction between hypersensitive sites in the active beta-globin locus.

Authors:  Bas Tolhuis; Robert Jan Palstra; Erik Splinter; Frank Grosveld; Wouter de Laat
Journal:  Mol Cell       Date:  2002-12       Impact factor: 17.970

3.  Formation of a tissue-specific histone acetylation pattern by the hematopoietic transcription factor GATA-1.

Authors:  Danielle L Letting; Carrie Rakowski; Mitchell J Weiss; Gerd A Blobel
Journal:  Mol Cell Biol       Date:  2003-02       Impact factor: 4.272

4.  A complex chromatin landscape revealed by patterns of nuclease sensitivity and histone modification within the mouse beta-globin locus.

Authors:  Michael Bulger; Dirk Schübeler; M A Bender; Joan Hamilton; Catherine M Farrell; Ross C Hardison; Mark Groudine
Journal:  Mol Cell Biol       Date:  2003-08       Impact factor: 4.272

Review 5.  The insulation of genes from external enhancers and silencing chromatin.

Authors:  Bonnie Burgess-Beusse; Catherine Farrell; Miklos Gaszner; Michael Litt; Vesco Mutskov; Felix Recillas-Targa; Melanie Simpson; Adam West; Gary Felsenfeld
Journal:  Proc Natl Acad Sci U S A       Date:  2002-08-01       Impact factor: 11.205

6.  The beta -globin locus control region (LCR) functions primarily by enhancing the transition from transcription initiation to elongation.

Authors:  Tomoyuki Sawado; Jessica Halow; M A Bender; Mark Groudine
Journal:  Genes Dev       Date:  2003-04-02       Impact factor: 11.361

7.  Long-range chromatin regulatory interactions in vivo.

Authors:  David Carter; Lyubomira Chakalova; Cameron S Osborne; Yan-feng Dai; Peter Fraser
Journal:  Nat Genet       Date:  2002-11-11       Impact factor: 38.330

8.  The beta-globin nuclear compartment in development and erythroid differentiation.

Authors:  Robert-Jan Palstra; Bas Tolhuis; Erik Splinter; Rian Nijmeijer; Frank Grosveld; Wouter de Laat
Journal:  Nat Genet       Date:  2003-09-21       Impact factor: 38.330

9.  Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin.

Authors:  Olaf Witt; Sven Monkemeyer; Gabi Rönndahl; Bernhard Erdlenbruch; Dirk Reinhardt; Katrin Kanbach; Arnulf Pekrun
Journal:  Blood       Date:  2002-10-17       Impact factor: 22.113

10.  Effects of 5-aza-2'-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease.

Authors:  Yogen Saunthararajah; Cheryl A Hillery; Don Lavelle; Robert Molokie; Louise Dorn; Linda Bressler; Stefana Gavazova; Yi-Hsiang Chen; Ronald Hoffman; Joseph DeSimone
Journal:  Blood       Date:  2003-08-07       Impact factor: 22.113
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  29 in total

1.  EHMT1 and EHMT2 inhibition induces fetal hemoglobin expression.

Authors:  Aline Renneville; Peter Van Galen; Matthew C Canver; Marie McConkey; John M Krill-Burger; David M Dorfman; Edward B Holson; Bradley E Bernstein; Stuart H Orkin; Daniel E Bauer; Benjamin L Ebert
Journal:  Blood       Date:  2015-08-28       Impact factor: 22.113

2.  Transcriptional environment and chromatin architecture interplay dictates globin expression patterns of heterospecific hybrids derived from undifferentiated human embryonic stem cells or from their erythroid progeny.

Authors:  Kai-Hsin Chang; Andy Huang; Hemei Han; Yi Jiang; Xiangdong Fang; Chao-Zhong Song; Steve Padilla; Hao Wang; Hongzhu Qu; John Stamatoyannopoulos; Qiliang Li; Thalia Papayannopoulou
Journal:  Exp Hematol       Date:  2013-08-28       Impact factor: 3.084

3.  Corepressor Rcor1 is essential for murine erythropoiesis.

Authors:  Huilan Yao; Devorah C Goldman; Tamilla Nechiporuk; Sunita Kawane; Shannon K McWeeney; Jeffrey W Tyner; Guang Fan; Marc A Kerenyi; Stuart H Orkin; William H Fleming; Gail Mandel
Journal:  Blood       Date:  2014-03-20       Impact factor: 22.113

4.  Heterochromatin Protein 1γ Is a Novel Epigenetic Repressor of Human Embryonic ϵ-Globin Gene Expression.

Authors:  Yadong Wang; Ying Wang; Lingling Ma; Min Nie; Junyi Ju; Ming Liu; Yexuan Deng; Bing Yao; Tao Gui; Xinyu Li; Chan Guo; Chi Ma; Renxiang Tan; Quan Zhao
Journal:  J Biol Chem       Date:  2017-02-01       Impact factor: 5.157

Review 5.  Regulation of chromatin by histone modifications.

Authors:  Andrew J Bannister; Tony Kouzarides
Journal:  Cell Res       Date:  2011-02-15       Impact factor: 25.617

6.  Gene induction and repression during terminal erythropoiesis are mediated by distinct epigenetic changes.

Authors:  Piu Wong; Shilpa M Hattangadi; Albert W Cheng; Garrett M Frampton; Richard A Young; Harvey F Lodish
Journal:  Blood       Date:  2011-08-22       Impact factor: 22.113

7.  Cytokine-mediated increases in fetal hemoglobin are associated with globin gene histone modification and transcription factor reprogramming.

Authors:  Orapan Sripichai; Christine M Kiefer; Natarajan V Bhanu; Toshihiko Tanno; Seung-Jae Noh; Sung-Ho Goh; J Eric Russell; Cheryl L Rognerud; Ching-Nan Ou; Patricia A Oneal; Emily R Meier; Nicole M Gantt; Colleen Byrnes; Y Terry Lee; Ann Dean; Jeffery L Miller
Journal:  Blood       Date:  2009-07-13       Impact factor: 22.113

8.  Maintenance of gene silencing by the coordinate action of the H3K9 methyltransferase G9a/KMT1C and the H3K4 demethylase Jarid1a/KDM5A.

Authors:  Chandra-Prakash Chaturvedi; Brinda Somasundaram; Kulwant Singh; Richard L Carpenedo; William L Stanford; F Jeffrey Dilworth; Marjorie Brand
Journal:  Proc Natl Acad Sci U S A       Date:  2012-10-29       Impact factor: 11.205

9.  Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells.

Authors:  Shuaiying Cui; Katarzyna E Kolodziej; Naoshi Obara; Alexandra Amaral-Psarris; Jeroen Demmers; Lihong Shi; James Douglas Engel; Frank Grosveld; John Strouboulis; Osamu Tanabe
Journal:  Mol Cell Biol       Date:  2011-06-13       Impact factor: 4.272

Review 10.  Analysis of epigenetic alterations to chromatin during development.

Authors:  Meghan E Minard; Abhinav K Jain; Michelle Craig Barton
Journal:  Genesis       Date:  2009-08       Impact factor: 2.487
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