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Literature DB >> 18755913

Preferential amplification of apoptotic DNA from plasma: potential for enhancing detection of minor DNA alterations in circulating DNA.

Harvey Mamon, Carlos Hader, Jin Li, Lilin Wang, Matthew Kulke, Giulia Amicarelli, Erlet Shehi, Daniel Adlerstein, Kristin Roper, Leah Killion, Susanne Hooshmand, G Mike Makrigiorgos.

Abstract

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 2008 PMID： 18755913 PMCID： PMC2984598 DOI： 10.1373/clinchem.2008.104612

Source DB: PubMed Journal: Clin Chem ISSN： 0009-9147 Impact factor: 8.327

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5 in total

1. Preferential isolation of fragmented DNA enhances the detection of circulating mutated k-ras DNA.

Authors: Mengjun Wang; Timothy M Block; Laura Steel; Dean E Brenner; Ying-Hsiu Su
Journal: Clin Chem Date: 2004-01 Impact factor: 8.327

2. Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms.

Authors: Ying Li; Bernhard Zimmermann; Corinne Rusterholz; Anjeung Kang; Wolfgang Holzgreve; Sinuhe Hahn
Journal: Clin Chem Date: 2004-04-08 Impact factor: 8.327

3. Whole genome amplification of plasma-circulating DNA enables expanded screening for allelic imbalance in plasma.

Authors: Jin Li; Lyndsay Harris; Harvey Mamon; Matthew H Kulke; Wei-Hua Liu; Penny Zhu; G Mike Makrigiorgos
Journal: J Mol Diagn Date: 2006-02 Impact factor: 5.568

4. DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells.

Authors: S Jahr; H Hentze; S Englisch; D Hardt; F O Fackelmayer; R D Hesch; R Knippers
Journal: Cancer Res Date: 2001-02-15 Impact factor: 12.701

5. FLAG assay as a novel method for real-time signal generation during PCR: application to detection and genotyping of KRAS codon 12 mutations.

Authors: Giulia Amicarelli; Erlet Shehi; G Mike Makrigiorgos; Daniel Adlerstein
Journal: Nucleic Acids Res Date: 2007-10-11 Impact factor: 16.971

5 in total

6 in total

Preferential amplification of apoptotic DNA from plasma: potential for enhancing detection of minor DNA alterations in circulating DNA.

1. Preferential isolation of fragmented DNA enhances the detection of circulating mutated k-ras DNA.

2. Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms.

3. Whole genome amplification of plasma-circulating DNA enables expanded screening for allelic imbalance in plasma.

4. DNA fragments in the blood plasma of cancer patients: quantitations and evidence for their origin from apoptotic and necrotic cells.

5. FLAG assay as a novel method for real-time signal generation during PCR: application to detection and genotyping of KRAS codon 12 mutations.

1. Single-tube, highly parallel mutation enrichment in cancer gene panels by use of temperature-tolerant COLD-PCR.

2. Noninvasive detection of EGFR T790M in gefitinib or erlotinib resistant non-small cell lung cancer.

3. Temperature-tolerant COLD-PCR reduces temperature stringency and enables robust mutation enrichment.

4. High fragmentation characterizes tumour-derived circulating DNA.

5. Origin and quantification of circulating DNA in mice with human colorectal cancer xenografts.

6. Direct quantification of cell-free, circulating DNA from unpurified plasma.